LINC00323 knockdown suppresses the proliferation, migration, and vascular mimicry of non-small cell lung cancer cells by promoting ubiquitinated degradation of AKAP1

LINC00323 knockdown suppresses the proliferation, migration, and vascular mimicry of non-small cell lung cancer cells by promoting ubiquitinated degradation of AKAP1

Background: LINC00323, a new long noncoding RNA, is aberrantly expressed in several cancers. However, the expression, function, and mechanism of LINC00323 in non-small cell lung cancer (NSCLC) are unclear. Methods: In the present study, LINC00323, VEGFA, microvessel density (MVD), and AKAP1 levels w...

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Bibliographic Details
Main Authors: Bin Ke, Hai Zhong, Yuxin Gong, Xiaofei Chen, Chenxin Yan, Lin Shi
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-04-01
Series:Non-coding RNA Research
Subjects:
Non-small cell lung cancer
LINC00323
Vascular mimicry
AKAP1
Ubiquitination
Online Access:http://www.sciencedirect.com/science/article/pii/S2468054024001707
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