Predicting recurrence and recurrence-free survival in initially unresectable hepatocellular carcinoma: a novel nomogram for patients undergoing conversion hepatectomy with lenvatinib, PD-1 inhibitor, and interventional therapy

Predicting recurrence and recurrence-free survival in initially unresectable hepatocellular carcinoma: a novel nomogram for patients undergoing conversion hepatectomy with lenvatinib, PD-1 inhibitor, and interventional therapy

PurposeThis research aims to develop prognostic nomograms to predict tumor recurrence and recurrence-free survival (RFS) in individuals with initially unresectable hepatocellular carcinoma (uHCC) who were later subjected to conversion hepatectomy following lenvatinib, PD-1 inhibitors, and interventi...

Full description

Saved in:

Bibliographic Details
Main Authors:	Cheng Xu, Zhihong Tang, Meng Wei, Danxi Liu, Qingqing Pang, Baishan Huang, Xinglin Mo, Feixiang Wu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Immunology
Subjects:	hepatocellular carcinoma hepatectomy recurrence recurrence-free survival nomogram model
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1602327/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Changes in perioperative serum transaminase levels: predicting early recurrence after hepatectomy for hepatocellular carcinoma
by: Yingfei Wei, et al.
Published: (2025-05-01)

Construction of a random survival forest model based on a machine learning algorithm to predict early recurrence after hepatectomy for adult hepatocellular carcinoma
by: Ji Zhang, et al.
Published: (2024-12-01)

Effect of 15- or 25-min intermittent Pringle maneuver on early recurrence of hepatocellular carcinoma after hepatectomy: a protocol for a randomized controlled trial
by: Xuehai Jia, et al.
Published: (2025-06-01)

Conversion hepatectomy for advanced hepatocellular carcinoma after right portal vein transection and lenvatinib therapy
by: Yuki Ohya, et al.
Published: (2020-12-01)

Prognostic significance of early and multiple recurrences after curative resection for hepatocellular carcinoma
by: Akihiro Tanemura, et al.
Published: (2024-10-01)

The independent prognostic nomogram models for primary and recurrent retroperitoneal liposarcoma: a population-based cohort study
by: Huan Deng, et al.
Published: (2025-08-01)

Characteristics recurrence pattern of cholangiolocellular carcinoma as intrahepatic bile duct tumor growth following curative resection: a case report
by: Keishi Hakoda, et al.
Published: (2019-09-01)

Nomogram for prediction of recurrence in patients with lumbar disc herniation after unilateral biportal endoscopy spinal surgery: a retrospective study
by: Yi Rong, et al.
Published: (2025-06-01)

Risk factors and nomogram predictive models for postsurgical progression/hyperprogression recurrence in hepatocellular carcinoma with macroscopic vascular invasion
by: Yiyue Huang, et al.
Published: (2024-11-01)

Nomogram Development for Assessing Oncotype DX Recurrence Scores in Breast Cancer: A Chinese Population Study
by: Jiayin Song, et al.
Published: (2025-03-01)

Prognostic nomogram for recurrence of hepatocellular carcinoma after liver transplantation for decision making on postoperative adjuvant therapy
by: Chen-Hao Gao, et al.
Published: (2025-07-01)

Predictive nomograms of repeat intrahepatic recurrence and overall survival after radiofrequency ablation of recurrent colorectal liver metastases
by: Ji-Chen Wang, et al.
Published: (2024-12-01)

Development of a LASSO machine learning algorithm-based model for postoperative delirium prediction in hepatectomy patients
by: Yu Zhu, et al.
Published: (2025-01-01)

A Nomogram for Predicting Recurrence in Stage I Non‐Small Cell Lung Cancer
by: Rongrong Bian, et al.
Published: (2024-11-01)

Development of a nomogram for predicting recurrence of epithelial ovarian cancer involving traditional Chinese medicine treatment
by: Xiaofeng Chen, et al.
Published: (2025-05-01)

A Nomogram Model for Predicting Recurrent Coronary Thrombosis in Kawasaki Disease Patients
by: Zhou X, et al.
Published: (2025-01-01)

Is there a role of surgical resection for uveal malignant melanoma liver metastases: report of two cases
by: Oğuzhan Şal, et al.
Published: (2025-05-01)

Development and validation of a nomogram for predicting hemoptysis recurrence in cystic bronchiectasis patients following bronchial artery embolization
by: Yuxin Duan, et al.
Published: (2025-05-01)

Nomograms for predicting recurrence of HER2‐positive breast cancer with different HR status based on ultrasound and clinicopathological characteristics
by: Xudong Zhang, et al.
Published: (2024-09-01)

Construction and validation of a nomogram model for predicting the risk of recurrence in patients with lower extremity arteriosclerosis obliterans after surgical intervention
by: Yanyan Lu, et al.
Published: (2025-04-01)

Predictors of recurrence after conversion therapy in unresectable hepatocellular carcinoma treated with HAIC, bevacizumab, and sintilimab
by: Chang-Fu Liu, et al.
Published: (2025-08-01)

Nomogram for predicting post-progression-free survival in patients with recurrent pancreatic ductal adenocarcinoma after radical surgery: a retrospective analysis
by: Dailei Qin, et al.
Published: (2024-12-01)

Development and validation of a nomogram to predict recurrence in epithelial ovarian cancer using complete blood count and lipid profiles
by: Xi Tang, et al.
Published: (2025-02-01)

Development and validation of an inflammation-nutrition indices-based nomogram for predicting early recurrence in patients with stage IB lung adenocarcinoma
by: Xianneng He, et al.
Published: (2024-10-01)

Factors affecting refractoriness or recurrence in diffuse large B-cell lymphoma: development and validation of a novel predictive nomogram
by: Yiwei Guo, et al.
Published: (2025-12-01)

Nomograms to predict the long‐time prognosis in patients with alpha‐fetoprotein negative hepatocellular carcinoma following radical resection
by: Jian Huang, et al.
Published: (2020-04-01)

Nomogram based on tumor burden score for prediction of prognosis of patients with hepatocellular carcinoma before hepatectomy
by: Qianru Xiao, et al.
Published: (2025-07-01)

Development and validation of a nomogram for predicting postoperative recurrent lumbar disc herniation after unilateral biportal endoscopic discectomy
by: Zhibin Xing, et al.
Published: (2025-07-01)

Risk factors and a nomogram model for recurrence of benign paroxysmal positional vertigo: a multicenter cross-sectional study
by: Qingchun Pan, et al.
Published: (2025-04-01)

Development and validation of a nomogram model for sleep disorders in patients with recurrent implantation failure based on physiological and lifestyle factors
by: You Zhang, et al.
Published: (2025-08-01)

Clinicopathological-based nomogram prediction and molecular characterization of postoperative recurrence in clinical T1 clear cell renal cell carcinoma
by: Zhao Yang, et al.
Published: (2025-06-01)

Biochemical recurrence prediction after robot-assited radical prostatectomy (BCR-PRARP)
by: Tanan Bejrananda, et al.
Published: (2025-01-01)

Machine learning-based ultrasound radiomics for predicting risk of recurrence in breast cancer
by: Wei Fan, et al.
Published: (2025-05-01)

Nomogram Based on Immune-Inflammatory Score and Classical Clinicopathological Parameters for Predicting the Recurrence of Endometrial Carcinoma: A Large, Multi-Center Retrospective Study
by: Wang Y, et al.
Published: (2024-12-01)

Periprostatic fat magnetic resonance imaging based radiomics nomogram for predicting biochemical recurrence-free survival in patients with non-metastatic prostate cancer after radical prostatectomy
by: Xiao-Hui Wu, et al.
Published: (2024-11-01)

Adjuvant Lenvatinib for High-Risk CNLC IIb/IIIa Hepatocellular Carcinoma After Curative Hepatectomy: A Prospective Exploratory Study
by: Sun HC, et al.
Published: (2025-05-01)

Classification of microvascular invasion of hepatocellular carcinoma: Different standards, common goals: Letter to the editor on “Classification of microvascular invasion of hepatocellular carcinoma: Correlation with prognosis and magnetic resonance imaging”
by: Wei Chen, et al.
Published: (2025-07-01)

Novel prediction nomogram model for recurrent/persistent disease versus the American thyroid association recurrence risk stratification in patients with N1b papillary thyroid cancer: a retrospective cohort study
by: Jin Liu, et al.
Published: (2025-08-01)

The value of prealbumin in predicting post hepatectomy liver failure for patients with hepatocellular carcinoma undergoing major hepatectomy
by: Hang-Dong Jia, et al.
Published: (2025-07-01)

Risk prediction of recurrent ischemic stroke based on Carotid Plaque-RADS: construction and validation of a nomogram model
by: Miao Qiao, et al.
Published: (2025-08-01)