Hypermethylation and increased expression of the DRD2 gene in schizophrenia

Hypermethylation and increased expression of the DRD2 gene in schizophrenia

Abstract Background Schizophrenia (SCZ) is one of the most serious mental disorders, and dysfunction of the dopamine system is a key pathological hypothesis for SCZ. The DRD2 gene is a risk gene for SCZ, and its methylation is also considered an important marker of SCZ. Among methylation sites of A...

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Main Authors: Lili Qing, Tiantian Zou, Wensa Yin, Run Wu, Tiantian Cheng, Haodi Yuan, Chen Zhou, Xuanyu Chen, Jia Wang, Ting Yang, Liping Hu, Linlin Liu, Shengjie Nie
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Psychiatry
Subjects:
Schizophrenia
DRD2 gene
DNA methylation
Gene expression
Online Access:https://doi.org/10.1186/s12888-025-07154-y
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