Nephrotoxic characteristics of anti-tuberculosis drugs

The review analyzes publications devoted to the frequency of renal adverse reactions during tuberculosis chemotherapy. The most significant pathophysiological mechanisms causing development of drug-induced nephrotoxicity are presented. The article describes the specific features of nephrotoxic effec...

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Main Authors: G. N. Mozhokina, A. G. Samoylova, Z. A. Zangieva
Format: Article
Language:Russian
Published: New Terra Publishing House 2019-11-01
Series:Туберкулез и болезни лёгких
Subjects:
Online Access:https://www.tibl-journal.com/jour/article/view/1347
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author G. N. Mozhokina
A. G. Samoylova
Z. A. Zangieva
author_facet G. N. Mozhokina
A. G. Samoylova
Z. A. Zangieva
author_sort G. N. Mozhokina
collection DOAJ
description The review analyzes publications devoted to the frequency of renal adverse reactions during tuberculosis chemotherapy. The most significant pathophysiological mechanisms causing development of drug-induced nephrotoxicity are presented. The article describes the specific features of nephrotoxic effect of aminoglycosides, capreomycin, rifampicin, pyrazinamide, fluoroquinolones, and linezolid. The authors concluded that it was necessary to perform clinical and laboratory monitoring of kidney function for the timely detection of nephrotoxic reactions.
format Article
id doaj-art-e52a586f651242959ca279d417b175df
institution OA Journals
issn 2075-1230
2542-1506
language Russian
publishDate 2019-11-01
publisher New Terra Publishing House
record_format Article
series Туберкулез и болезни лёгких
spelling doaj-art-e52a586f651242959ca279d417b175df2025-08-20T01:47:52ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062019-11-019710596510.21292/2075-1230-2019-97-10-59-651347Nephrotoxic characteristics of anti-tuberculosis drugsG. N. Mozhokina0A. G. Samoylova1Z. A. Zangieva2National Medical Research Center of Phthisiopulmonology and Infectious DiseasesNational Medical Research Center of Phthisiopulmonology and Infectious DiseasesNational Medical Research Center of Phthisiopulmonology and Infectious DiseasesThe review analyzes publications devoted to the frequency of renal adverse reactions during tuberculosis chemotherapy. The most significant pathophysiological mechanisms causing development of drug-induced nephrotoxicity are presented. The article describes the specific features of nephrotoxic effect of aminoglycosides, capreomycin, rifampicin, pyrazinamide, fluoroquinolones, and linezolid. The authors concluded that it was necessary to perform clinical and laboratory monitoring of kidney function for the timely detection of nephrotoxic reactions.https://www.tibl-journal.com/jour/article/view/1347adverse eventsnephrotoxicityanti-tuberculosis drugs
spellingShingle G. N. Mozhokina
A. G. Samoylova
Z. A. Zangieva
Nephrotoxic characteristics of anti-tuberculosis drugs
Туберкулез и болезни лёгких
adverse events
nephrotoxicity
anti-tuberculosis drugs
title Nephrotoxic characteristics of anti-tuberculosis drugs
title_full Nephrotoxic characteristics of anti-tuberculosis drugs
title_fullStr Nephrotoxic characteristics of anti-tuberculosis drugs
title_full_unstemmed Nephrotoxic characteristics of anti-tuberculosis drugs
title_short Nephrotoxic characteristics of anti-tuberculosis drugs
title_sort nephrotoxic characteristics of anti tuberculosis drugs
topic adverse events
nephrotoxicity
anti-tuberculosis drugs
url https://www.tibl-journal.com/jour/article/view/1347
work_keys_str_mv AT gnmozhokina nephrotoxiccharacteristicsofantituberculosisdrugs
AT agsamoylova nephrotoxiccharacteristicsofantituberculosisdrugs
AT zazangieva nephrotoxiccharacteristicsofantituberculosisdrugs