NOD1 deficiency promotes inflammation via autophagic degradation of ASK1
Abstract Nucleotide-binding oligomerization domain-containing protein 1 (NOD1) is a pattern recognition receptor of bacterial peptidoglycans. NOD1 facilitates the elimination of invading intracellular bacteria via autophagy induction. Here, we demonstrate that NOD1 exerts an anti-inflammatory effect...
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| Main Authors: | Yoshitaka Kimura, Miyako Kimura, Noriko Miura, Yusuke Yoshino, Hajime Kono |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-025-08213-6 |
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