Routine blood tests in early pregnancy: their development and value in the early diagnosis of gestational diabetes mellitus

With the change in China’s second-child fertility policy, the numbers of older pregnant women and high-risk pregnancies have significantly increased, and the incidence of gestational diabetes mellitus (GDM) is likely to rise. GDM can cause a variety of adverse pregnancy outcomes, seriously threaten...

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Main Authors: Guo-Lin Liu, Ning-Zhi Zhang
Format: Article
Language:English
Published: IMR Press 2021-04-01
Series:Clinical and Experimental Obstetrics & Gynecology
Subjects:
Online Access:https://www.imrpress.com/journal/CEOG/48/2/10.31083/j.ceog.2021.02.2273
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author Guo-Lin Liu
Ning-Zhi Zhang
author_facet Guo-Lin Liu
Ning-Zhi Zhang
author_sort Guo-Lin Liu
collection DOAJ
description With the change in China’s second-child fertility policy, the numbers of older pregnant women and high-risk pregnancies have significantly increased, and the incidence of gestational diabetes mellitus (GDM) is likely to rise. GDM can cause a variety of adverse pregnancy outcomes, seriously threaten the safety of perinatal mothers and infants, and affect the long-term health of mothers and their offspring. Currently, the GDM screening period is between 24 to 28 weeks of pregnancy, but there are some shortcomings in screening at this time, since because of late diagnosis, the best time for intervention and treatment for some high-risk pregnant women may be delayed. Studies have shown that early prediction and early diagnosis of GDM is of great significance to improve pregnancy outcomes, so it is important to investigate early pregnancy prediction indexes of GDM to improve the screening efficiency for GDM and improve the management of GDM. It has been found that blood cell parameters, inflammatory factors, fat metabolism indices and liver enzyme metabolism markers have specific early predictive value for GDM. The application of these parameters combined with significant independent risk factors in the early prediction and early diagnosis of GDM will be of great value in the prevention and treatment of GDM and the prognosis of mothers and infants. This article reviews the development of routine blood test parameters during pregnancy and their value in the early diagnosis of GDM.
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spelling doaj-art-e522c4bd00ec43dcb10ca07958047fa02025-08-20T02:04:30ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632021-04-0148222823310.31083/j.ceog.2021.02.2273S0390-6663(21)00074-9Routine blood tests in early pregnancy: their development and value in the early diagnosis of gestational diabetes mellitusGuo-Lin Liu0Ning-Zhi Zhang1Fu Yang People’s Hospital, No. 63 Lu Ci Street, Yingzhou District, 236000 Fuyang, Anhui Province, ChinaFu Yang People’s Hospital, No. 63 Lu Ci Street, Yingzhou District, 236000 Fuyang, Anhui Province, ChinaWith the change in China’s second-child fertility policy, the numbers of older pregnant women and high-risk pregnancies have significantly increased, and the incidence of gestational diabetes mellitus (GDM) is likely to rise. GDM can cause a variety of adverse pregnancy outcomes, seriously threaten the safety of perinatal mothers and infants, and affect the long-term health of mothers and their offspring. Currently, the GDM screening period is between 24 to 28 weeks of pregnancy, but there are some shortcomings in screening at this time, since because of late diagnosis, the best time for intervention and treatment for some high-risk pregnant women may be delayed. Studies have shown that early prediction and early diagnosis of GDM is of great significance to improve pregnancy outcomes, so it is important to investigate early pregnancy prediction indexes of GDM to improve the screening efficiency for GDM and improve the management of GDM. It has been found that blood cell parameters, inflammatory factors, fat metabolism indices and liver enzyme metabolism markers have specific early predictive value for GDM. The application of these parameters combined with significant independent risk factors in the early prediction and early diagnosis of GDM will be of great value in the prevention and treatment of GDM and the prognosis of mothers and infants. This article reviews the development of routine blood test parameters during pregnancy and their value in the early diagnosis of GDM.https://www.imrpress.com/journal/CEOG/48/2/10.31083/j.ceog.2021.02.2273gestational diabetes mellitusroutine blood testearly diagnosis
spellingShingle Guo-Lin Liu
Ning-Zhi Zhang
Routine blood tests in early pregnancy: their development and value in the early diagnosis of gestational diabetes mellitus
Clinical and Experimental Obstetrics & Gynecology
gestational diabetes mellitus
routine blood test
early diagnosis
title Routine blood tests in early pregnancy: their development and value in the early diagnosis of gestational diabetes mellitus
title_full Routine blood tests in early pregnancy: their development and value in the early diagnosis of gestational diabetes mellitus
title_fullStr Routine blood tests in early pregnancy: their development and value in the early diagnosis of gestational diabetes mellitus
title_full_unstemmed Routine blood tests in early pregnancy: their development and value in the early diagnosis of gestational diabetes mellitus
title_short Routine blood tests in early pregnancy: their development and value in the early diagnosis of gestational diabetes mellitus
title_sort routine blood tests in early pregnancy their development and value in the early diagnosis of gestational diabetes mellitus
topic gestational diabetes mellitus
routine blood test
early diagnosis
url https://www.imrpress.com/journal/CEOG/48/2/10.31083/j.ceog.2021.02.2273
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AT ningzhizhang routinebloodtestsinearlypregnancytheirdevelopmentandvalueintheearlydiagnosisofgestationaldiabetesmellitus