Research advances of dual-specificity phosphatases in kidney disease
Belonging to the family of protein tyrosine phosphatases,DUSPs（dual-specificity phosphatases）can dephosphorylate both serine/threonine and tyrosine residues concurrently.In recent years,with the in-depth study of DUSPs,they have been implicated as major participants in various physiological and path...
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| Format: | Article |
| Language: | zho |
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Editorial Department of Journal of Clinical Nephrology
2021-01-01
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| Series: | Linchuang shenzangbing zazhi |
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| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57905610&Fpath=home&index=0 |
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| author | 杜宇 章波 赵景宏 |
| author_facet | 杜宇 章波 赵景宏 |
| author_sort | 杜宇 |
| collection | DOAJ |
| description | Belonging to the family of protein tyrosine phosphatases,DUSPs（dual-specificity phosphatases）can dephosphorylate both serine/threonine and tyrosine residues concurrently.In recent years,with the in-depth study of DUSPs,they have been implicated as major participants in various physiological and pathological activities.And DUSPs related to MAPK（mitogen-activated protein kinase）play a vital regulatory role in a variety of kidney diseases.This review summarized the general characteristics and current researches of DUSPs in nephrology. |
| format | Article |
| id | doaj-art-e5148f3bd4494592be95dd5334aaff3b |
| institution | Kabale University |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2021-01-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-e5148f3bd4494592be95dd5334aaff3b2025-08-20T03:48:58ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902021-01-0115716157905610Research advances of dual-specificity phosphatases in kidney disease杜宇章波赵景宏Belonging to the family of protein tyrosine phosphatases,DUSPs（dual-specificity phosphatases）can dephosphorylate both serine/threonine and tyrosine residues concurrently.In recent years,with the in-depth study of DUSPs,they have been implicated as major participants in various physiological and pathological activities.And DUSPs related to MAPK（mitogen-activated protein kinase）play a vital regulatory role in a variety of kidney diseases.This review summarized the general characteristics and current researches of DUSPs in nephrology.http://www.lcszb.com/thesisDetails?columnId=57905610&Fpath=home&index=0Dual-specificity phosphatasesMitogen-activated protein kinaseKidney disease |
| spellingShingle | 杜宇 章波 赵景宏 Research advances of dual-specificity phosphatases in kidney disease Linchuang shenzangbing zazhi Dual-specificity phosphatases Mitogen-activated protein kinase Kidney disease |
| title | Research advances of dual-specificity phosphatases in kidney disease |
| title_full | Research advances of dual-specificity phosphatases in kidney disease |
| title_fullStr | Research advances of dual-specificity phosphatases in kidney disease |
| title_full_unstemmed | Research advances of dual-specificity phosphatases in kidney disease |
| title_short | Research advances of dual-specificity phosphatases in kidney disease |
| title_sort | research advances of dual specificity phosphatases in kidney disease |
| topic | Dual-specificity phosphatases Mitogen-activated protein kinase Kidney disease |
| url | http://www.lcszb.com/thesisDetails?columnId=57905610&Fpath=home&index=0 |
| work_keys_str_mv | AT dùyǔ researchadvancesofdualspecificityphosphatasesinkidneydisease AT zhāngbō researchadvancesofdualspecificityphosphatasesinkidneydisease AT zhàojǐnghóng researchadvancesofdualspecificityphosphatasesinkidneydisease |