Research advances of dual-specificity phosphatases in kidney disease
Belonging to the family of protein tyrosine phosphatases,DUSPs（dual-specificity phosphatases）can dephosphorylate both serine/threonine and tyrosine residues concurrently.In recent years,with the in-depth study of DUSPs,they have been implicated as major participants in various physiological and path...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Nephrology
2021-01-01
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| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57905610&Fpath=home&index=0 |
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| Summary: | Belonging to the family of protein tyrosine phosphatases,DUSPs（dual-specificity phosphatases）can dephosphorylate both serine/threonine and tyrosine residues concurrently.In recent years,with the in-depth study of DUSPs,they have been implicated as major participants in various physiological and pathological activities.And DUSPs related to MAPK（mitogen-activated protein kinase）play a vital regulatory role in a variety of kidney diseases.This review summarized the general characteristics and current researches of DUSPs in nephrology. |
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| ISSN: | 1671-2390 |