Cytokine Signaling in Diabetic Neuropathy: A Key Player in Peripheral Nerve Damage

Cytokine Signaling in Diabetic Neuropathy: A Key Player in Peripheral Nerve Damage

Diabetic peripheral neuropathy (DPN) is a debilitating complication of diabetes mellitus, characterized by progressive nerve damage driven by chronic hyperglycemia and systemic inflammation. The pathophysiology of DPN is significantly influenced by pro-inflammatory cytokines, such as IL-1β, IL-6, an...

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Bibliographic Details
Main Authors: Zahra Nashtahosseini, Majid Eslami, Elham Paraandavaji, Alireza Haraj, Bahram Fadaee Dowlat, Ehsan Hosseinzadeh, Valentyn Oksenych, Ramtin Naderian
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Biomedicines
Subjects:
cytokine signaling
diabetic peripheral neuropathy (DPN)
peripheral nerve damage
inflammation
biomarker
Online Access:https://www.mdpi.com/2227-9059/13/3/589
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