Using Natural Language Processing to Identify Symptomatic Adverse Events in Pediatric Oncology: Tutorial for Clinician Researchers
AbstractArtificial intelligence (AI) is poised to become an integral component in health care research and delivery, promising to address complex challenges with unprecedented efficiency and precision. However, many clinicians lack training and experience with AI, and for those who wish t...
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| Format: | Article |
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JMIR Publications
2025-07-01
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| Series: | JMIR Bioinformatics and Biotechnology |
| Online Access: | https://bioinform.jmir.org/2025/1/e70751 |
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| author | Clifton P Thornton Maryam Daniali Lei Wang Spandana Makeneni Allison Barz Leahy |
| author_facet | Clifton P Thornton Maryam Daniali Lei Wang Spandana Makeneni Allison Barz Leahy |
| author_sort | Clifton P Thornton |
| collection | DOAJ |
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AbstractArtificial intelligence (AI) is poised to become an integral component in health care research and delivery, promising to address complex challenges with unprecedented efficiency and precision. However, many clinicians lack training and experience with AI, and for those who wish to incorporate AI into research and practice, the path forward remains unclear. Technical barriers, institutional constraints, and lack of familiarity with computer and data science frequently stall progress. In this tutorial, we present a transparent account of our experiences as a newly established interdisciplinary team of clinical oncology researchers and data scientists working to develop a natural language processing model to identify symptomatic adverse events during pediatric cancer therapy. We outline the key steps for clinicians to consider as they explore the utility of AI in their inquiry and practice, including building a digital laboratory, curating a large clinical dataset, and developing early-stage AI models. We emphasize the invaluable role of institutional support, including financial and logistical resources, and dedicated and innovative computer and data scientists as equal partners in the research team. Our account highlights both facilitators and barriers encountered spanning financial support, learning curves inherent with interdisciplinary collaboration, and constraints of time and personnel. Through this narrative tutorial, we intend to demystify the process of AI research and equip clinicians with actionable steps to initiate new ventures in oncology research. As AI continues to reshape the research and practice landscapes, sharing insights from past successes and challenges will be essential to informing a clear path forward. |
| format | Article |
| id | doaj-art-e509d56f7bb14fdeaa7c49a0aa94520f |
| institution | DOAJ |
| issn | 2563-3570 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | JMIR Publications |
| record_format | Article |
| series | JMIR Bioinformatics and Biotechnology |
| spelling | doaj-art-e509d56f7bb14fdeaa7c49a0aa94520f2025-08-20T02:55:03ZengJMIR PublicationsJMIR Bioinformatics and Biotechnology2563-35702025-07-016e70751e7075110.2196/70751Using Natural Language Processing to Identify Symptomatic Adverse Events in Pediatric Oncology: Tutorial for Clinician ResearchersClifton P Thorntonhttp://orcid.org/0000-0002-7130-7777Maryam Danialihttp://orcid.org/0000-0003-1093-9612Lei Wanghttp://orcid.org/0000-0003-4415-1268Spandana Makenenihttp://orcid.org/0009-0002-2769-4172Allison Barz Leahyhttp://orcid.org/0000-0002-1368-4064 AbstractArtificial intelligence (AI) is poised to become an integral component in health care research and delivery, promising to address complex challenges with unprecedented efficiency and precision. However, many clinicians lack training and experience with AI, and for those who wish to incorporate AI into research and practice, the path forward remains unclear. Technical barriers, institutional constraints, and lack of familiarity with computer and data science frequently stall progress. In this tutorial, we present a transparent account of our experiences as a newly established interdisciplinary team of clinical oncology researchers and data scientists working to develop a natural language processing model to identify symptomatic adverse events during pediatric cancer therapy. We outline the key steps for clinicians to consider as they explore the utility of AI in their inquiry and practice, including building a digital laboratory, curating a large clinical dataset, and developing early-stage AI models. We emphasize the invaluable role of institutional support, including financial and logistical resources, and dedicated and innovative computer and data scientists as equal partners in the research team. Our account highlights both facilitators and barriers encountered spanning financial support, learning curves inherent with interdisciplinary collaboration, and constraints of time and personnel. Through this narrative tutorial, we intend to demystify the process of AI research and equip clinicians with actionable steps to initiate new ventures in oncology research. As AI continues to reshape the research and practice landscapes, sharing insights from past successes and challenges will be essential to informing a clear path forward.https://bioinform.jmir.org/2025/1/e70751 |
| spellingShingle | Clifton P Thornton Maryam Daniali Lei Wang Spandana Makeneni Allison Barz Leahy Using Natural Language Processing to Identify Symptomatic Adverse Events in Pediatric Oncology: Tutorial for Clinician Researchers JMIR Bioinformatics and Biotechnology |
| title | Using Natural Language Processing to Identify Symptomatic Adverse Events in Pediatric Oncology: Tutorial for Clinician Researchers |
| title_full | Using Natural Language Processing to Identify Symptomatic Adverse Events in Pediatric Oncology: Tutorial for Clinician Researchers |
| title_fullStr | Using Natural Language Processing to Identify Symptomatic Adverse Events in Pediatric Oncology: Tutorial for Clinician Researchers |
| title_full_unstemmed | Using Natural Language Processing to Identify Symptomatic Adverse Events in Pediatric Oncology: Tutorial for Clinician Researchers |
| title_short | Using Natural Language Processing to Identify Symptomatic Adverse Events in Pediatric Oncology: Tutorial for Clinician Researchers |
| title_sort | using natural language processing to identify symptomatic adverse events in pediatric oncology tutorial for clinician researchers |
| url | https://bioinform.jmir.org/2025/1/e70751 |
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