Single‐Cell Analysis Integrated With Machine Learning Elucidates the Mechanisms of Nucleus Pulposus Cells Apoptosis in Intervertebral Disc Degeneration and Therapeutic Interventions

Single‐Cell Analysis Integrated With Machine Learning Elucidates the Mechanisms of Nucleus Pulposus Cells Apoptosis in Intervertebral Disc Degeneration and Therapeutic Interventions

ABSTRACT Background The molecular of intervertebral disc degeneration (IVDD) is still unclear. When it comes to treating decoction, traditional Chinese medicine is effective. In particular, the Duhuo (Radix Angelicae Biseratae) may be particularly helpful. Purpose To identify nucleus pulposus cells...

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Bibliographic Details
Main Authors: Chao Song, Xiaofei Wu, Chaoqi Chen, Baoxin Shen, Yongliang Mei, Qian Yan, Feng Jiang, Feng Chen, Fei Liu
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:JOR Spine
Subjects:
apoptosis
Duhuo
immune infiltration
intervertebral disc degeneration
macrophage
Online Access:https://doi.org/10.1002/jsp2.70036
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https://doi.org/10.1002/jsp2.70036

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