Transcriptional Activation of p53 during Cold Induced Torpor in the 13-Lined Ground Squirrel Ictidomys tridecemlineatus

The transcription factor p53 is located at the centre of multiple pathways relating the cellular response to stress. Commonly known as a tumor suppressor, it is responsible for initiating diverse actions to protect the integrity of the genome, ranging from cell cycle arrest to apoptosis. This study...

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Bibliographic Details
Main Authors: Joshua Hefler, Cheng-Wei Wu, Kenneth B. Storey
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Biochemistry Research International
Online Access:http://dx.doi.org/10.1155/2015/731595
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