Antibiotic Prophylaxis and Treatment for Cardiac Device Infections

Cardiac device infections (CDIs) are a serious complication in patients with implanted devices, resulting in increased morbidity, prolonged hospital stay, and increased healthcare costs. The effective management of these infections involves a combination of appropriate antibiotic therapy and prevent...

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Main Authors: Claudio Pandozi, Andrea Matteucci, Carlo Pignalberi, Luca Sgarra, Michela Bonanni, Marco Valerio Mariani, Vincenzo Mirco La Fazia, Lorenzo Nesti, Stefania Angela Di Fusco, Federico Nardi, Furio Colivicchi
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Antibiotics
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Online Access:https://www.mdpi.com/2079-6382/13/10/991
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author Claudio Pandozi
Andrea Matteucci
Carlo Pignalberi
Luca Sgarra
Michela Bonanni
Marco Valerio Mariani
Vincenzo Mirco La Fazia
Lorenzo Nesti
Stefania Angela Di Fusco
Federico Nardi
Furio Colivicchi
author_facet Claudio Pandozi
Andrea Matteucci
Carlo Pignalberi
Luca Sgarra
Michela Bonanni
Marco Valerio Mariani
Vincenzo Mirco La Fazia
Lorenzo Nesti
Stefania Angela Di Fusco
Federico Nardi
Furio Colivicchi
author_sort Claudio Pandozi
collection DOAJ
description Cardiac device infections (CDIs) are a serious complication in patients with implanted devices, resulting in increased morbidity, prolonged hospital stay, and increased healthcare costs. The effective management of these infections involves a combination of appropriate antibiotic therapy and preventive strategies aimed at reducing the risk of infection. The role of antibiotic prophylaxis in infection prevention is crucial, including the emerging use of antibiotic-supported tools and other local antibiotic delivery systems, which may reduce the risk of infection at the device implant site. In this contemporary review, we provide an overview of the prophylactic treatment and different antibiotic regimens for the treatment of CDIs, emphasizing early diagnosis, appropriate choice of antibiotics, and individualized treatment.
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language English
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publisher MDPI AG
record_format Article
series Antibiotics
spelling doaj-art-e502e94138f24c89b3735b30ced138292025-08-20T02:11:04ZengMDPI AGAntibiotics2079-63822024-10-01131099110.3390/antibiotics13100991Antibiotic Prophylaxis and Treatment for Cardiac Device InfectionsClaudio Pandozi0Andrea Matteucci1Carlo Pignalberi2Luca Sgarra3Michela Bonanni4Marco Valerio Mariani5Vincenzo Mirco La Fazia6Lorenzo Nesti7Stefania Angela Di Fusco8Federico Nardi9Furio Colivicchi10Clinical and Rehabilitation Cardiology Division, San Filippo Neri Hospital, 00135 Rome, ItalyClinical and Rehabilitation Cardiology Division, San Filippo Neri Hospital, 00135 Rome, ItalyClinical and Rehabilitation Cardiology Division, San Filippo Neri Hospital, 00135 Rome, ItalyCardiology Department, Regional General Hospital “F. Miulli”, 70021 Bari, ItalyDepartment of Experimental Medicine, Tor Vergata University, 00133 Rome, ItalyDepartment of Cardiovascular, Respiratory, Nephrological, Aenesthesiological and Geriatric Sciences “Sapienza” University of Rome, 00185 Rome, ItalyTexas Cardiac Arrhythmia Institute, St. David’s Medical Center, Austin, TX 78705, USACardiopulmonary Lab, Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, ItalyClinical and Rehabilitation Cardiology Division, San Filippo Neri Hospital, 00135 Rome, ItalySanto Spirito Hospital, 15033 Casale Monferrato, ItalyClinical and Rehabilitation Cardiology Division, San Filippo Neri Hospital, 00135 Rome, ItalyCardiac device infections (CDIs) are a serious complication in patients with implanted devices, resulting in increased morbidity, prolonged hospital stay, and increased healthcare costs. The effective management of these infections involves a combination of appropriate antibiotic therapy and preventive strategies aimed at reducing the risk of infection. The role of antibiotic prophylaxis in infection prevention is crucial, including the emerging use of antibiotic-supported tools and other local antibiotic delivery systems, which may reduce the risk of infection at the device implant site. In this contemporary review, we provide an overview of the prophylactic treatment and different antibiotic regimens for the treatment of CDIs, emphasizing early diagnosis, appropriate choice of antibiotics, and individualized treatment.https://www.mdpi.com/2079-6382/13/10/991cardiovascular implantable electronic devicesCIED infectionantibiotic prophylaxisantibiotic treatments
spellingShingle Claudio Pandozi
Andrea Matteucci
Carlo Pignalberi
Luca Sgarra
Michela Bonanni
Marco Valerio Mariani
Vincenzo Mirco La Fazia
Lorenzo Nesti
Stefania Angela Di Fusco
Federico Nardi
Furio Colivicchi
Antibiotic Prophylaxis and Treatment for Cardiac Device Infections
Antibiotics
cardiovascular implantable electronic devices
CIED infection
antibiotic prophylaxis
antibiotic treatments
title Antibiotic Prophylaxis and Treatment for Cardiac Device Infections
title_full Antibiotic Prophylaxis and Treatment for Cardiac Device Infections
title_fullStr Antibiotic Prophylaxis and Treatment for Cardiac Device Infections
title_full_unstemmed Antibiotic Prophylaxis and Treatment for Cardiac Device Infections
title_short Antibiotic Prophylaxis and Treatment for Cardiac Device Infections
title_sort antibiotic prophylaxis and treatment for cardiac device infections
topic cardiovascular implantable electronic devices
CIED infection
antibiotic prophylaxis
antibiotic treatments
url https://www.mdpi.com/2079-6382/13/10/991
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