Adherence to HIV post-exposure prophylaxis in a specialized service in São Paulo, Brazil
Introduction: The effectiveness of human immunodeficiency virus (HIV) post-exposure prophylaxis (PEP) depends on adherence to the protocol, which includes taking antiretrovirals (ARVs) and attending visits. We examined the adherence rate to antiretroviral agents and follow-up visits identifying the...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The Journal of Infection in Developing Countries
2023-06-01
|
| Series: | Journal of Infection in Developing Countries |
| Subjects: | |
| Online Access: | https://jidc.org/index.php/journal/article/view/17515 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850148613295964160 |
|---|---|
| author | Marcos Morais Santos Silva Luciane Simões Duarte Lucia Yasuko Izumi Nichiata |
| author_facet | Marcos Morais Santos Silva Luciane Simões Duarte Lucia Yasuko Izumi Nichiata |
| author_sort | Marcos Morais Santos Silva |
| collection | DOAJ |
| description |
Introduction: The effectiveness of human immunodeficiency virus (HIV) post-exposure prophylaxis (PEP) depends on adherence to the protocol, which includes taking antiretrovirals (ARVs) and attending visits. We examined the adherence rate to antiretroviral agents and follow-up visits identifying the associated characteristics of adherence and the reasons for not attending HIV PEP consultations in a specialized service in São Paulo, Brazil.
Methodology: This was a cross-sectional study with health service users who had an indication for PEP due to sexual exposure in an HIV/AIDS service from April to October 2019. The health service users were followed-up throughout the prophylaxis cycle. Adherence was determined through self-reports on antiretroviral agent use and attendance to follow-up consultations.
Results: Association measures were employed to identify adherence-related characteristics. The sample analyzed included 91 users. The mean age was 32.5 years old (SD = 9.8). The largest share was white-skinned (49.5%), men who have sex with other men (62.2%), male (86.8%), and undergraduate/graduate students (65.9%). Adherence totaled 56.7% and health insurance was the associated characteristic (p = 0.039). Work (55.9%), using a private service (15.2%), forgetfulness (11.8%) and considering follow-up unnecessary (11.8%) were the main reasons for not attending the follow-up appointments.
Conclusions: Few users do attend HIV PEP consultations. The users without health insurance had the highest adherence percentage whereas work was mentioned as a reason for not attending HIV PEP consultations.
|
| format | Article |
| id | doaj-art-e500c8889b8d4addbd2dfec87871af27 |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2023-06-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-e500c8889b8d4addbd2dfec87871af272025-08-20T02:27:11ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802023-06-01170610.3855/jidc.17515Adherence to HIV post-exposure prophylaxis in a specialized service in São Paulo, BrazilMarcos Morais Santos Silva0Luciane Simões Duarte1Lucia Yasuko Izumi Nichiata2Public Health Nursing Department, School of Nursing, University of São Paulo, São Paulo, BrazilChronic Noncommunicable Diseases, Division of Disease Control Coordination of São Paulo State Department of Health, São Paulo, BrazilPublic Health Nursing Department, School of Nursing, University of São Paulo, São Paulo, Brazil Introduction: The effectiveness of human immunodeficiency virus (HIV) post-exposure prophylaxis (PEP) depends on adherence to the protocol, which includes taking antiretrovirals (ARVs) and attending visits. We examined the adherence rate to antiretroviral agents and follow-up visits identifying the associated characteristics of adherence and the reasons for not attending HIV PEP consultations in a specialized service in São Paulo, Brazil. Methodology: This was a cross-sectional study with health service users who had an indication for PEP due to sexual exposure in an HIV/AIDS service from April to October 2019. The health service users were followed-up throughout the prophylaxis cycle. Adherence was determined through self-reports on antiretroviral agent use and attendance to follow-up consultations. Results: Association measures were employed to identify adherence-related characteristics. The sample analyzed included 91 users. The mean age was 32.5 years old (SD = 9.8). The largest share was white-skinned (49.5%), men who have sex with other men (62.2%), male (86.8%), and undergraduate/graduate students (65.9%). Adherence totaled 56.7% and health insurance was the associated characteristic (p = 0.039). Work (55.9%), using a private service (15.2%), forgetfulness (11.8%) and considering follow-up unnecessary (11.8%) were the main reasons for not attending the follow-up appointments. Conclusions: Few users do attend HIV PEP consultations. The users without health insurance had the highest adherence percentage whereas work was mentioned as a reason for not attending HIV PEP consultations. https://jidc.org/index.php/journal/article/view/17515HIVmedicationadherencepost-exposure prophylaxisanti-retroviral agents |
| spellingShingle | Marcos Morais Santos Silva Luciane Simões Duarte Lucia Yasuko Izumi Nichiata Adherence to HIV post-exposure prophylaxis in a specialized service in São Paulo, Brazil Journal of Infection in Developing Countries HIV medication adherence post-exposure prophylaxis anti-retroviral agents |
| title | Adherence to HIV post-exposure prophylaxis in a specialized service in São Paulo, Brazil |
| title_full | Adherence to HIV post-exposure prophylaxis in a specialized service in São Paulo, Brazil |
| title_fullStr | Adherence to HIV post-exposure prophylaxis in a specialized service in São Paulo, Brazil |
| title_full_unstemmed | Adherence to HIV post-exposure prophylaxis in a specialized service in São Paulo, Brazil |
| title_short | Adherence to HIV post-exposure prophylaxis in a specialized service in São Paulo, Brazil |
| title_sort | adherence to hiv post exposure prophylaxis in a specialized service in sao paulo brazil |
| topic | HIV medication adherence post-exposure prophylaxis anti-retroviral agents |
| url | https://jidc.org/index.php/journal/article/view/17515 |
| work_keys_str_mv | AT marcosmoraissantossilva adherencetohivpostexposureprophylaxisinaspecializedserviceinsaopaulobrazil AT lucianesimoesduarte adherencetohivpostexposureprophylaxisinaspecializedserviceinsaopaulobrazil AT luciayasukoizuminichiata adherencetohivpostexposureprophylaxisinaspecializedserviceinsaopaulobrazil |