Retinal Hyperreflective Foci Are Biomarkers of Ocular Disease: A Scoping Review With Evidence From Humans and Insights From Animal Models
Conclusion: There is an agreement that HRF of less than 30 μm are biomarkers of inflammation in the retina despite having variable intraretinal locations. HRF resulting from the effect of aging can be discerned from AMD based on their quantity and appearance. The results show the importance of HRF a...
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/joph/9573587 |
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| author | Mohd N. Mat Nor Colin R. Green David Squirrell Monica L. Acosta |
| author_facet | Mohd N. Mat Nor Colin R. Green David Squirrell Monica L. Acosta |
| author_sort | Mohd N. Mat Nor |
| collection | DOAJ |
| description | Conclusion: There is an agreement that HRF of less than 30 μm are biomarkers of inflammation in the retina despite having variable intraretinal locations. HRF resulting from the effect of aging can be discerned from AMD based on their quantity and appearance. The results show the importance of HRF as a biomarker of ocular disease and confirm that HRF are indicative of an inflammatory eye disorder. |
| format | Article |
| id | doaj-art-e4fd3eaa043a41c6a71a7aeb7c6cf220 |
| institution | Kabale University |
| issn | 2090-0058 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-e4fd3eaa043a41c6a71a7aeb7c6cf2202025-08-20T03:26:16ZengWileyJournal of Ophthalmology2090-00582025-01-01202510.1155/joph/9573587Retinal Hyperreflective Foci Are Biomarkers of Ocular Disease: A Scoping Review With Evidence From Humans and Insights From Animal ModelsMohd N. Mat Nor0Colin R. Green1David Squirrell2Monica L. Acosta3School of Optometry and Vision ScienceDepartment of OphthalmologyAuckland District Health BoardSchool of Optometry and Vision ScienceConclusion: There is an agreement that HRF of less than 30 μm are biomarkers of inflammation in the retina despite having variable intraretinal locations. HRF resulting from the effect of aging can be discerned from AMD based on their quantity and appearance. The results show the importance of HRF as a biomarker of ocular disease and confirm that HRF are indicative of an inflammatory eye disorder.http://dx.doi.org/10.1155/joph/9573587 |
| spellingShingle | Mohd N. Mat Nor Colin R. Green David Squirrell Monica L. Acosta Retinal Hyperreflective Foci Are Biomarkers of Ocular Disease: A Scoping Review With Evidence From Humans and Insights From Animal Models Journal of Ophthalmology |
| title | Retinal Hyperreflective Foci Are Biomarkers of Ocular Disease: A Scoping Review With Evidence From Humans and Insights From Animal Models |
| title_full | Retinal Hyperreflective Foci Are Biomarkers of Ocular Disease: A Scoping Review With Evidence From Humans and Insights From Animal Models |
| title_fullStr | Retinal Hyperreflective Foci Are Biomarkers of Ocular Disease: A Scoping Review With Evidence From Humans and Insights From Animal Models |
| title_full_unstemmed | Retinal Hyperreflective Foci Are Biomarkers of Ocular Disease: A Scoping Review With Evidence From Humans and Insights From Animal Models |
| title_short | Retinal Hyperreflective Foci Are Biomarkers of Ocular Disease: A Scoping Review With Evidence From Humans and Insights From Animal Models |
| title_sort | retinal hyperreflective foci are biomarkers of ocular disease a scoping review with evidence from humans and insights from animal models |
| url | http://dx.doi.org/10.1155/joph/9573587 |
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