Metastasis of Malignant Melanoma to Urinary Bladder: A Case Report and Review of the Literature

Aims. Metastatic malignant melanoma of the urinary bladder is a rare clinical entity, with only twenty-three published cases to date. We present a case of this rare entity, a thorough review of the literature, and differential diagnosis of melanoma in the bladder. Methods and Results. A 55-year-old...

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Main Authors: Rashna Meunier, Gyan Pareek, Ali Amin
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2015/173870
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author Rashna Meunier
Gyan Pareek
Ali Amin
author_facet Rashna Meunier
Gyan Pareek
Ali Amin
author_sort Rashna Meunier
collection DOAJ
description Aims. Metastatic malignant melanoma of the urinary bladder is a rare clinical entity, with only twenty-three published cases to date. We present a case of this rare entity, a thorough review of the literature, and differential diagnosis of melanoma in the bladder. Methods and Results. A 55-year-old woman with a history of malignant melanoma of the right thigh, excised eight years ago, presented with back pain, fatigue, and hematuria. She underwent computed tomography (CT) scan and was found to have metastases within the liver, spleen, lungs, and urinary bladder. She underwent cystoscopy and transurethral resection of three polypoid lesions. Histologic and immunohistochemical examination revealed metastatic malignant melanoma involving bladder mucosa. Conclusions. This case illustrates the importance of including malignant melanoma in the differential diagnosis of high grade neoplasms of bladder, especially in cases where the relevant clinical history is not available.
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spelling doaj-art-e4f8937b1f284fb8b87aa13e7a93139b2025-08-20T02:21:19ZengWileyCase Reports in Pathology2090-67812090-679X2015-01-01201510.1155/2015/173870173870Metastasis of Malignant Melanoma to Urinary Bladder: A Case Report and Review of the LiteratureRashna Meunier0Gyan Pareek1Ali Amin2Department of Pathology and Laboratory Medicine, Rhode Island Hospital, The Warren Alpert Medical School, Brown University, Providence, RI 02903, USAUniversity Urological Associates, The Warren Alpert Medical School, Brown University, Providence, RI 02904, USADepartment of Pathology and Laboratory Medicine, Rhode Island Hospital, The Warren Alpert Medical School, Brown University, Providence, RI 02903, USAAims. Metastatic malignant melanoma of the urinary bladder is a rare clinical entity, with only twenty-three published cases to date. We present a case of this rare entity, a thorough review of the literature, and differential diagnosis of melanoma in the bladder. Methods and Results. A 55-year-old woman with a history of malignant melanoma of the right thigh, excised eight years ago, presented with back pain, fatigue, and hematuria. She underwent computed tomography (CT) scan and was found to have metastases within the liver, spleen, lungs, and urinary bladder. She underwent cystoscopy and transurethral resection of three polypoid lesions. Histologic and immunohistochemical examination revealed metastatic malignant melanoma involving bladder mucosa. Conclusions. This case illustrates the importance of including malignant melanoma in the differential diagnosis of high grade neoplasms of bladder, especially in cases where the relevant clinical history is not available.http://dx.doi.org/10.1155/2015/173870
spellingShingle Rashna Meunier
Gyan Pareek
Ali Amin
Metastasis of Malignant Melanoma to Urinary Bladder: A Case Report and Review of the Literature
Case Reports in Pathology
title Metastasis of Malignant Melanoma to Urinary Bladder: A Case Report and Review of the Literature
title_full Metastasis of Malignant Melanoma to Urinary Bladder: A Case Report and Review of the Literature
title_fullStr Metastasis of Malignant Melanoma to Urinary Bladder: A Case Report and Review of the Literature
title_full_unstemmed Metastasis of Malignant Melanoma to Urinary Bladder: A Case Report and Review of the Literature
title_short Metastasis of Malignant Melanoma to Urinary Bladder: A Case Report and Review of the Literature
title_sort metastasis of malignant melanoma to urinary bladder a case report and review of the literature
url http://dx.doi.org/10.1155/2015/173870
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