Facial assessment methods for inhibiting glycation and aging effects and the correlation between glycation and aging parameters
Abstract This study aimed to develop in vivo methods for assessing facial anti-glycation and anti-aging effects and to investigate the link between glycation and aging signs. We utilized an AGE reader to measure AGEs levels on the face and arms, establishing a correlation to validate the reader’s us...
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| Language: | English |
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Nature Portfolio
2025-01-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-025-86467-0 |
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| author | Qin Zhang Dangdang Cheng Feifei Wang |
| author_facet | Qin Zhang Dangdang Cheng Feifei Wang |
| author_sort | Qin Zhang |
| collection | DOAJ |
| description | Abstract This study aimed to develop in vivo methods for assessing facial anti-glycation and anti-aging effects and to investigate the link between glycation and aging signs. We utilized an AGE reader to measure AGEs levels on the face and arms, establishing a correlation to validate the reader’s use for facial AGEs detection. Then the product’s 7-day anti-glycation effect was evaluated. And its 56-day anti-aging effects were evaluated using non-invasive probes and VISIA CR, assessing skin tone (skin brightness L* and yellowness b*, skin gloss), texture (skin elasticity R2 and firmness F4, skin pores), and hydration (skin moisture content). Correlations between facial AGEs levels and aging parameters were analyzed. Results indicated a strong correlation between facial and arm AGEs after product application, supporting facial AGEs level as an assessment parameter. The product demonstrated substantial anti-glycation and anti-aging effects, suggesting the methods’ efficacy for cosmetic evaluation. A stronger overall correlation was found between AGEs levels and skin tone than with skin texture and hydration, highlighting glycation’s impact on skin color. |
| format | Article |
| id | doaj-art-e4f783aeedad48d3b449d44b9bb0d962 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-e4f783aeedad48d3b449d44b9bb0d9622025-01-19T12:24:02ZengNature PortfolioScientific Reports2045-23222025-01-0115111010.1038/s41598-025-86467-0Facial assessment methods for inhibiting glycation and aging effects and the correlation between glycation and aging parametersQin Zhang0Dangdang Cheng1Feifei Wang2Shanghai Jiyan Biomedical Development Co., Ltd.Shanghai Jiyan Biomedical Development Co., Ltd.Yunnan Characteristic Plant Extraction Laboratory, Yunnan Yunke Characteristic Plant Extraction Laboratory Co., LtdAbstract This study aimed to develop in vivo methods for assessing facial anti-glycation and anti-aging effects and to investigate the link between glycation and aging signs. We utilized an AGE reader to measure AGEs levels on the face and arms, establishing a correlation to validate the reader’s use for facial AGEs detection. Then the product’s 7-day anti-glycation effect was evaluated. And its 56-day anti-aging effects were evaluated using non-invasive probes and VISIA CR, assessing skin tone (skin brightness L* and yellowness b*, skin gloss), texture (skin elasticity R2 and firmness F4, skin pores), and hydration (skin moisture content). Correlations between facial AGEs levels and aging parameters were analyzed. Results indicated a strong correlation between facial and arm AGEs after product application, supporting facial AGEs level as an assessment parameter. The product demonstrated substantial anti-glycation and anti-aging effects, suggesting the methods’ efficacy for cosmetic evaluation. A stronger overall correlation was found between AGEs levels and skin tone than with skin texture and hydration, highlighting glycation’s impact on skin color.https://doi.org/10.1038/s41598-025-86467-0AGE readerAnti-glycation evaluationAnti-aging evaluationGlycation-aging correlation |
| spellingShingle | Qin Zhang Dangdang Cheng Feifei Wang Facial assessment methods for inhibiting glycation and aging effects and the correlation between glycation and aging parameters Scientific Reports AGE reader Anti-glycation evaluation Anti-aging evaluation Glycation-aging correlation |
| title | Facial assessment methods for inhibiting glycation and aging effects and the correlation between glycation and aging parameters |
| title_full | Facial assessment methods for inhibiting glycation and aging effects and the correlation between glycation and aging parameters |
| title_fullStr | Facial assessment methods for inhibiting glycation and aging effects and the correlation between glycation and aging parameters |
| title_full_unstemmed | Facial assessment methods for inhibiting glycation and aging effects and the correlation between glycation and aging parameters |
| title_short | Facial assessment methods for inhibiting glycation and aging effects and the correlation between glycation and aging parameters |
| title_sort | facial assessment methods for inhibiting glycation and aging effects and the correlation between glycation and aging parameters |
| topic | AGE reader Anti-glycation evaluation Anti-aging evaluation Glycation-aging correlation |
| url | https://doi.org/10.1038/s41598-025-86467-0 |
| work_keys_str_mv | AT qinzhang facialassessmentmethodsforinhibitingglycationandagingeffectsandthecorrelationbetweenglycationandagingparameters AT dangdangcheng facialassessmentmethodsforinhibitingglycationandagingeffectsandthecorrelationbetweenglycationandagingparameters AT feifeiwang facialassessmentmethodsforinhibitingglycationandagingeffectsandthecorrelationbetweenglycationandagingparameters |