INFLUENCE OF MENOPAUSE ON BLOOD PRESSURE DIPPING IN WOMEN WITH METABOLIC SYNDROME: A CASE-CONTROL STUDY

Aim. To study if menopause influences the blood pressure (BP) decrease level during nighttime in women with metabolic syndrome.Methods. 84 women with metabolic syndrome are examined, from them 52 are in postmenopause (average age is 56 [SD 5] years) and 32 are in premenopause (average age is 44 [5]...

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Main Authors: D. A. Anichkov, N. A. Shostak
Format: Article
Language:English
Published: Столичная издательская компания 2015-12-01
Series:Рациональная фармакотерапия в кардиологии
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Online Access:https://www.rpcardio.online/jour/article/view/347
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author D. A. Anichkov
N. A. Shostak
author_facet D. A. Anichkov
N. A. Shostak
author_sort D. A. Anichkov
collection DOAJ
description Aim. To study if menopause influences the blood pressure (BP) decrease level during nighttime in women with metabolic syndrome.Methods. 84 women with metabolic syndrome are examined, from them 52 are in postmenopause (average age is 56 [SD 5] years) and 32 are in premenopause (average age is 44 [5] years). Anthropomorphic measurements were made, levels of office BP and heart rate were assessed, ambulatory BP monitoring was carried out, lipids and glucose of blood serum were studied.Results. Clinical parameters, characterizing metabolic syndrome, didn’t vary between the groups. Number of patients with insufficient decrease of BP in postmenopausal women didn’t differ significantly from the number of such women in premenopausal period (for systolic BP: 64% versus 52%, p=0,288; for diastolic BP: 34% versus 42%, p=0,469). Nevertheless, when evaluating the level of systolic BP decrease during nighttime as continuous variable, significant differences between groups are revealed (M±SEM [95% CI]: 4.4±1.5% [1.4-7.3] in postmenopausal women versus 11.3±1.7% [7.9-14.8] in premenopausal women, p=0,011).Conclusion. Postmenopause associates with insufficient systolic BP decrease during nighttime in women with metabolic syndrome.
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2225-3653
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series Рациональная фармакотерапия в кардиологии
spelling doaj-art-e4eddc37af894270aacbf757863f6d9e2025-08-23T10:00:18ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-12-011291310.20996/1819-6446-2005-1-2-9-13347INFLUENCE OF MENOPAUSE ON BLOOD PRESSURE DIPPING IN WOMEN WITH METABOLIC SYNDROME: A CASE-CONTROL STUDYD. A. Anichkov0N. A. Shostak1Russian State Medical University, MoscowRussian State Medical University, MoscowAim. To study if menopause influences the blood pressure (BP) decrease level during nighttime in women with metabolic syndrome.Methods. 84 women with metabolic syndrome are examined, from them 52 are in postmenopause (average age is 56 [SD 5] years) and 32 are in premenopause (average age is 44 [5] years). Anthropomorphic measurements were made, levels of office BP and heart rate were assessed, ambulatory BP monitoring was carried out, lipids and glucose of blood serum were studied.Results. Clinical parameters, characterizing metabolic syndrome, didn’t vary between the groups. Number of patients with insufficient decrease of BP in postmenopausal women didn’t differ significantly from the number of such women in premenopausal period (for systolic BP: 64% versus 52%, p=0,288; for diastolic BP: 34% versus 42%, p=0,469). Nevertheless, when evaluating the level of systolic BP decrease during nighttime as continuous variable, significant differences between groups are revealed (M±SEM [95% CI]: 4.4±1.5% [1.4-7.3] in postmenopausal women versus 11.3±1.7% [7.9-14.8] in premenopausal women, p=0,011).Conclusion. Postmenopause associates with insufficient systolic BP decrease during nighttime in women with metabolic syndrome.https://www.rpcardio.online/jour/article/view/347menopauseambulatory bp monitoring (abpm)metabolic syndrome
spellingShingle D. A. Anichkov
N. A. Shostak
INFLUENCE OF MENOPAUSE ON BLOOD PRESSURE DIPPING IN WOMEN WITH METABOLIC SYNDROME: A CASE-CONTROL STUDY
Рациональная фармакотерапия в кардиологии
menopause
ambulatory bp monitoring (abpm)
metabolic syndrome
title INFLUENCE OF MENOPAUSE ON BLOOD PRESSURE DIPPING IN WOMEN WITH METABOLIC SYNDROME: A CASE-CONTROL STUDY
title_full INFLUENCE OF MENOPAUSE ON BLOOD PRESSURE DIPPING IN WOMEN WITH METABOLIC SYNDROME: A CASE-CONTROL STUDY
title_fullStr INFLUENCE OF MENOPAUSE ON BLOOD PRESSURE DIPPING IN WOMEN WITH METABOLIC SYNDROME: A CASE-CONTROL STUDY
title_full_unstemmed INFLUENCE OF MENOPAUSE ON BLOOD PRESSURE DIPPING IN WOMEN WITH METABOLIC SYNDROME: A CASE-CONTROL STUDY
title_short INFLUENCE OF MENOPAUSE ON BLOOD PRESSURE DIPPING IN WOMEN WITH METABOLIC SYNDROME: A CASE-CONTROL STUDY
title_sort influence of menopause on blood pressure dipping in women with metabolic syndrome a case control study
topic menopause
ambulatory bp monitoring (abpm)
metabolic syndrome
url https://www.rpcardio.online/jour/article/view/347
work_keys_str_mv AT daanichkov influenceofmenopauseonbloodpressuredippinginwomenwithmetabolicsyndromeacasecontrolstudy
AT nashostak influenceofmenopauseonbloodpressuredippinginwomenwithmetabolicsyndromeacasecontrolstudy