Nomogram M Prognostic Value for Major Adverse Cardiac and Cerebral Events after Elective Cardiac Surgery with Cardiopulmonary Bypass

The objective: to evaluate the prognostic value of Nomogram M for major adverse cardiac events (MACE) and major adverse cardiac and cerebral events (MACCE) after elective cardiac surgery with cardiopulmonary bypass.Subjects and Methods. This is a retrospective cohort study of the Nomogram M prognost...

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Main Authors: L. B. Berikashvili, A. N. Kuzovlev, M. Yа. Yadgarov, K. K. Kadantseva, E. A. Ozhiganova, V. V. Likhvantsev
Format: Article
Language:Russian
Published: New Terra Publishing House 2022-05-01
Series:Вестник анестезиологии и реаниматологии
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Online Access:https://www.vair-journal.com/jour/article/view/643
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author L. B. Berikashvili
A. N. Kuzovlev
M. Yа. Yadgarov
K. K. Kadantseva
E. A. Ozhiganova
V. V. Likhvantsev
author_facet L. B. Berikashvili
A. N. Kuzovlev
M. Yа. Yadgarov
K. K. Kadantseva
E. A. Ozhiganova
V. V. Likhvantsev
author_sort L. B. Berikashvili
collection DOAJ
description The objective: to evaluate the prognostic value of Nomogram M for major adverse cardiac events (MACE) and major adverse cardiac and cerebral events (MACCE) after elective cardiac surgery with cardiopulmonary bypass.Subjects and Methods. This is a retrospective cohort study of the Nomogram M prognostic value for MACE and MACCE after elective cardiac surgery with cardiopulmonary bypass. 158 patients were enrolled in the study. The prognostic value was estimated using ROC-analysis.Results. The frequency of MACE and MACCE during hospitalization made 5.7% (9 of 158 patients) and 6.3% (10 of 158 patients), respectively. AUC Nomogram M for MACE was 0.888 [0.825; 0.950] (p < 0.001). Cut-off value made 12.5 points (sensitivity – 88.89%, specificity – 83.89%). Odd ratio was 41.67 [95% CI 4.98; 348.61] (p < 0.001).AUC Nomogram M for MACCE was 0.893 [0.834; 0.951] (p < 0.001). Cut-off value made 12.5 points (sensitivity – 90.00%, specificity – 84.46%). Odd ratio was 48.91 [95% CI 5.91; 404.78] (p < 0.001)Conclusion. Nomogram M has a good prognostic value for the occurrence of MACE and MACCE after elective cardiac surgery with cardiopulmonary bypass. For MACE sensitivity made 88.89%, and specificity – 83.89%. For MACCE sensitivity was 90.00%, specificity – 84.46%.
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institution Kabale University
issn 2078-5658
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language Russian
publishDate 2022-05-01
publisher New Terra Publishing House
record_format Article
series Вестник анестезиологии и реаниматологии
spelling doaj-art-e4e89b0413b74237a6ea675dad72cf272025-08-20T03:56:32ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532022-05-0119261310.21292/2078-5658-2022-19-2-6-13504Nomogram M Prognostic Value for Major Adverse Cardiac and Cerebral Events after Elective Cardiac Surgery with Cardiopulmonary BypassL. B. Berikashvili0A. N. Kuzovlev1M. Yа. Yadgarov2K. K. Kadantseva3E. A. Ozhiganova4V. V. Likhvantsev5V. A. Negovsky Reanimatology Research Institute; M. F. Vladimirsky Moscow Regional Research and Clinical InstituteV. A. Negovsky Reanimatology Research InstituteV. A. Negovsky Reanimatology Research InstituteV. A. Negovsky Reanimatology Research InstituteV. A. Negovsky Reanimatology Research InstituteV. A. Negovsky Reanimatology Research Institute; I. M. Sechenov First Moscow State Medical University (Sechenov University)The objective: to evaluate the prognostic value of Nomogram M for major adverse cardiac events (MACE) and major adverse cardiac and cerebral events (MACCE) after elective cardiac surgery with cardiopulmonary bypass.Subjects and Methods. This is a retrospective cohort study of the Nomogram M prognostic value for MACE and MACCE after elective cardiac surgery with cardiopulmonary bypass. 158 patients were enrolled in the study. The prognostic value was estimated using ROC-analysis.Results. The frequency of MACE and MACCE during hospitalization made 5.7% (9 of 158 patients) and 6.3% (10 of 158 patients), respectively. AUC Nomogram M for MACE was 0.888 [0.825; 0.950] (p < 0.001). Cut-off value made 12.5 points (sensitivity – 88.89%, specificity – 83.89%). Odd ratio was 41.67 [95% CI 4.98; 348.61] (p < 0.001).AUC Nomogram M for MACCE was 0.893 [0.834; 0.951] (p < 0.001). Cut-off value made 12.5 points (sensitivity – 90.00%, specificity – 84.46%). Odd ratio was 48.91 [95% CI 5.91; 404.78] (p < 0.001)Conclusion. Nomogram M has a good prognostic value for the occurrence of MACE and MACCE after elective cardiac surgery with cardiopulmonary bypass. For MACE sensitivity made 88.89%, and specificity – 83.89%. For MACCE sensitivity was 90.00%, specificity – 84.46%.https://www.vair-journal.com/jour/article/view/643cardiac surgerycardiopulmonary bypassmacemaccepostoperative complicationsprognostic scales
spellingShingle L. B. Berikashvili
A. N. Kuzovlev
M. Yа. Yadgarov
K. K. Kadantseva
E. A. Ozhiganova
V. V. Likhvantsev
Nomogram M Prognostic Value for Major Adverse Cardiac and Cerebral Events after Elective Cardiac Surgery with Cardiopulmonary Bypass
Вестник анестезиологии и реаниматологии
cardiac surgery
cardiopulmonary bypass
mace
macce
postoperative complications
prognostic scales
title Nomogram M Prognostic Value for Major Adverse Cardiac and Cerebral Events after Elective Cardiac Surgery with Cardiopulmonary Bypass
title_full Nomogram M Prognostic Value for Major Adverse Cardiac and Cerebral Events after Elective Cardiac Surgery with Cardiopulmonary Bypass
title_fullStr Nomogram M Prognostic Value for Major Adverse Cardiac and Cerebral Events after Elective Cardiac Surgery with Cardiopulmonary Bypass
title_full_unstemmed Nomogram M Prognostic Value for Major Adverse Cardiac and Cerebral Events after Elective Cardiac Surgery with Cardiopulmonary Bypass
title_short Nomogram M Prognostic Value for Major Adverse Cardiac and Cerebral Events after Elective Cardiac Surgery with Cardiopulmonary Bypass
title_sort nomogram m prognostic value for major adverse cardiac and cerebral events after elective cardiac surgery with cardiopulmonary bypass
topic cardiac surgery
cardiopulmonary bypass
mace
macce
postoperative complications
prognostic scales
url https://www.vair-journal.com/jour/article/view/643
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