Circadian rest‐activity rhythm as an objective biomarker of patient‐reported outcomes in patients with advanced cancer

Circadian rest‐activity rhythm as an objective biomarker of patient‐reported outcomes in patients with advanced cancer

Abstract Background Psychosocial symptoms often cluster together, are refractory to treatment, and impair health‐related quality of life (HR‐QoL) in cancer patients. The contribution of circadian rhythm alterations to systemic symptoms has been overlooked in cancer, despite a causal link shown under...

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Main Authors: Pasquale F. Innominato, Sandra Komarzynski, Oxana G. Palesh, Robert Dallmann, Georg A. Bjarnason, Sylvie Giacchetti, Ayhan Ulusakarya, Mohamed Bouchahda, Mazen Haydar, Annabelle Ballesta, Abdoulaye Karaboué, Nicholas I. Wreglesworth, David Spiegel, Francis A. Lévi
Format: Article
Language:English
Published: Wiley 2018-09-01
Series:Cancer Medicine
Subjects:
actigraphy
Circadian
patient‐reported outcome
quality of life
symptom
Online Access:https://doi.org/10.1002/cam4.1711
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