Oesophageal eosinophilia and oesophageal diseases in children: are the limits clear?

Gastro-oesophageal reflux disease, eosinophilic oesophagitis and oesophageal motility disorders are among the most common diseases accompanying oesophageal eosinophilia. They have similarities and their limits are frequently not well defined. This article reviews the main characteristics relating to...

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Main Authors: Angel A Escobedo, Oscar Manuel Villa Jiménez, Sarah Esther Diaz-Oliva, Idalmis Aguilera-Matos
Format: Article
Language:English
Published: BMJ Publishing Group 2020-02-01
Series:BMJ Paediatrics Open
Online Access:https://bmjpaedsopen.bmj.com/content/4/1/e000680.full
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author Angel A Escobedo
Oscar Manuel Villa Jiménez
Sarah Esther Diaz-Oliva
Idalmis Aguilera-Matos
author_facet Angel A Escobedo
Oscar Manuel Villa Jiménez
Sarah Esther Diaz-Oliva
Idalmis Aguilera-Matos
author_sort Angel A Escobedo
collection DOAJ
description Gastro-oesophageal reflux disease, eosinophilic oesophagitis and oesophageal motility disorders are among the most common diseases accompanying oesophageal eosinophilia. They have similarities and their limits are frequently not well defined. This article reviews the main characteristics relating to their similarities and differences, highlighting existing controversies among these diseases, in addition to current knowledge. In the case of a patient with symptoms of oesophageal dysfunction, it is suggested to carry out an integral analysis of the clinical features and diagnostic test results, including histology, while individualising each case before confirming a definitive diagnosis. Future investigation in paediatric patients is necessary to assess eosinophilic infiltration in the various layers of the oesophageal tissue, along with its clinical and pathophysiological implications.
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issn 2399-9772
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publishDate 2020-02-01
publisher BMJ Publishing Group
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series BMJ Paediatrics Open
spelling doaj-art-e4dd2a22695049cda32a33dc80a1a5002025-08-20T02:07:13ZengBMJ Publishing GroupBMJ Paediatrics Open2399-97722020-02-014110.1136/bmjpo-2020-000680Oesophageal eosinophilia and oesophageal diseases in children: are the limits clear?Angel A Escobedo0Oscar Manuel Villa Jiménez1Sarah Esther Diaz-Oliva2Idalmis Aguilera-Matos3Epidemiology, Institute of Gastro-enterology, Havana City, La Habana, CubaInstitute of Gastroenterology, Havana, CubaPediatric Gastroentrology, Institute of Gastroenterology, Havana, CubaPediatric Gastroentrology, Institute of Gastroenterology, Havana, CubaGastro-oesophageal reflux disease, eosinophilic oesophagitis and oesophageal motility disorders are among the most common diseases accompanying oesophageal eosinophilia. They have similarities and their limits are frequently not well defined. This article reviews the main characteristics relating to their similarities and differences, highlighting existing controversies among these diseases, in addition to current knowledge. In the case of a patient with symptoms of oesophageal dysfunction, it is suggested to carry out an integral analysis of the clinical features and diagnostic test results, including histology, while individualising each case before confirming a definitive diagnosis. Future investigation in paediatric patients is necessary to assess eosinophilic infiltration in the various layers of the oesophageal tissue, along with its clinical and pathophysiological implications.https://bmjpaedsopen.bmj.com/content/4/1/e000680.full
spellingShingle Angel A Escobedo
Oscar Manuel Villa Jiménez
Sarah Esther Diaz-Oliva
Idalmis Aguilera-Matos
Oesophageal eosinophilia and oesophageal diseases in children: are the limits clear?
BMJ Paediatrics Open
title Oesophageal eosinophilia and oesophageal diseases in children: are the limits clear?
title_full Oesophageal eosinophilia and oesophageal diseases in children: are the limits clear?
title_fullStr Oesophageal eosinophilia and oesophageal diseases in children: are the limits clear?
title_full_unstemmed Oesophageal eosinophilia and oesophageal diseases in children: are the limits clear?
title_short Oesophageal eosinophilia and oesophageal diseases in children: are the limits clear?
title_sort oesophageal eosinophilia and oesophageal diseases in children are the limits clear
url https://bmjpaedsopen.bmj.com/content/4/1/e000680.full
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