Pharmacokinetics of Local Anesthetics in Dentistry: The Example of Articaine-Containing and Mepivacaine- Containing Anesthetics

Aim. To analyze current data on the pharmacokinetics of drugs used for local anesthesia in dental practice, with particular emphasis on articaine-containing and mepivacaine-containing anesthetics.   Materials and Methods. The study of up-to-date information from the Cyberleninka, Elibrary, Google Sc...

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Main Authors: A. Machin, S. A. Fokina, T. A. Mityushkina, K. Yu. Filippov, E. K. Korovushkina
Format: Article
Language:Russian
Published: LLC "Endo Press" 2024-01-01
Series:Эндодонтия Today
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Online Access:https://www.endodont.ru/jour/article/view/1257
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author A. Machin
S. A. Fokina
T. A. Mityushkina
K. Yu. Filippov
E. K. Korovushkina
author_facet A. Machin
S. A. Fokina
T. A. Mityushkina
K. Yu. Filippov
E. K. Korovushkina
author_sort A. Machin
collection DOAJ
description Aim. To analyze current data on the pharmacokinetics of drugs used for local anesthesia in dental practice, with particular emphasis on articaine-containing and mepivacaine-containing anesthetics.   Materials and Methods. The study of up-to-date information from the Cyberleninka, Elibrary, Google Scholar and PubMed electronic databases was carried out during a systematic review of the literature. Selected and included articles, the content of which concerns the pharmacokinetics of local anesthetics articaine and mepivacaine.   Results. 55 publications were reviewed. After analyzing the literature for inclusion criteria, the total number of publications has become 42.   Conclusions. According to the analyzed data, the choice of local anaesthetic solution should be made individually for each patient and be based on the pharmacokinetics of the drug.
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institution Kabale University
issn 1683-2981
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language Russian
publishDate 2024-01-01
publisher LLC "Endo Press"
record_format Article
series Эндодонтия Today
spelling doaj-art-e4d4177bb2e7483caf1534d6760117592025-08-20T03:59:02ZrusLLC "Endo Press"Эндодонтия Today1683-29811726-72422024-01-0121428128610.36377/1683-2981-2023-21-4-281-2861049Pharmacokinetics of Local Anesthetics in Dentistry: The Example of Articaine-Containing and Mepivacaine- Containing AnestheticsA. Machin0S. A. Fokina1T. A. Mityushkina2K. Yu. Filippov3E. K. Korovushkina4Hebrew Jerusalem UniversityRUDN UniversityRUDN UniversityRUDN UniversityRUDN UniversityAim. To analyze current data on the pharmacokinetics of drugs used for local anesthesia in dental practice, with particular emphasis on articaine-containing and mepivacaine-containing anesthetics.   Materials and Methods. The study of up-to-date information from the Cyberleninka, Elibrary, Google Scholar and PubMed electronic databases was carried out during a systematic review of the literature. Selected and included articles, the content of which concerns the pharmacokinetics of local anesthetics articaine and mepivacaine.   Results. 55 publications were reviewed. After analyzing the literature for inclusion criteria, the total number of publications has become 42.   Conclusions. According to the analyzed data, the choice of local anaesthetic solution should be made individually for each patient and be based on the pharmacokinetics of the drug.https://www.endodont.ru/jour/article/view/1257local anestheticsarticainemepivacainepharmacokinetics
spellingShingle A. Machin
S. A. Fokina
T. A. Mityushkina
K. Yu. Filippov
E. K. Korovushkina
Pharmacokinetics of Local Anesthetics in Dentistry: The Example of Articaine-Containing and Mepivacaine- Containing Anesthetics
Эндодонтия Today
local anesthetics
articaine
mepivacaine
pharmacokinetics
title Pharmacokinetics of Local Anesthetics in Dentistry: The Example of Articaine-Containing and Mepivacaine- Containing Anesthetics
title_full Pharmacokinetics of Local Anesthetics in Dentistry: The Example of Articaine-Containing and Mepivacaine- Containing Anesthetics
title_fullStr Pharmacokinetics of Local Anesthetics in Dentistry: The Example of Articaine-Containing and Mepivacaine- Containing Anesthetics
title_full_unstemmed Pharmacokinetics of Local Anesthetics in Dentistry: The Example of Articaine-Containing and Mepivacaine- Containing Anesthetics
title_short Pharmacokinetics of Local Anesthetics in Dentistry: The Example of Articaine-Containing and Mepivacaine- Containing Anesthetics
title_sort pharmacokinetics of local anesthetics in dentistry the example of articaine containing and mepivacaine containing anesthetics
topic local anesthetics
articaine
mepivacaine
pharmacokinetics
url https://www.endodont.ru/jour/article/view/1257
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