Inflammation and macrophage polarization are associated with Modic change type in lumbar radiculopathy
Introduction: Lumbar disc herniation (LDH) typically manifests as sciatica, attributed to nerve root mechanical compression and/or inflammation. Modic changes (MC), classified as type I or type II, are deemed to represent endplate vascular insufficiency and are hypothesized to create an inflammatory...
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| Main Authors: | Wensen Li, Niek Djuric, Christiaan Mink, Carmen L.A. Vleggeert-Lankamp |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
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| Series: | Brain and Spine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772529425000682 |
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