Inflammation and macrophage polarization are associated with Modic change type in lumbar radiculopathy

Introduction: Lumbar disc herniation (LDH) typically manifests as sciatica, attributed to nerve root mechanical compression and/or inflammation. Modic changes (MC), classified as type I or type II, are deemed to represent endplate vascular insufficiency and are hypothesized to create an inflammatory...

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Bibliographic Details
Main Authors: Wensen Li, Niek Djuric, Christiaan Mink, Carmen L.A. Vleggeert-Lankamp
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Brain and Spine
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772529425000682
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