Murine Double Minute 2–Positive Primary Pulmonary Artery Intimal Sarcoma Diagnosed by Pulmonary Arterial Catheter Aspiration After Emergency Admission
We present a rare case of primary pulmonary artery intimal sarcoma diagnosed after emergency admission for respiratory failure in an 80-year-old man. Tumor cells were obtained through minimally invasive pulmonary arterial catheter aspiration at a high-intensity magnetic resonance–diffusion-weighted...
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| Format: | Article |
| Language: | English |
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American College of Physicians
2024-07-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2023.1088 |
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| author | Makoto Hibino Shigehiro Watanabe Riko Kamada Shunichi Tobe Kazunari Maeda Shigeto Horiuchi Noriyoshi Ishikawa Tadashi Hasegawa Tetsuri Kondo |
| author_facet | Makoto Hibino Shigehiro Watanabe Riko Kamada Shunichi Tobe Kazunari Maeda Shigeto Horiuchi Noriyoshi Ishikawa Tadashi Hasegawa Tetsuri Kondo |
| author_sort | Makoto Hibino |
| collection | DOAJ |
| description | We present a rare case of primary pulmonary artery intimal sarcoma diagnosed after emergency admission for respiratory failure in an 80-year-old man. Tumor cells were obtained through minimally invasive pulmonary arterial catheter aspiration at a high-intensity magnetic resonance–diffusion-weighted imaging–highlighted site. Despite the patient's poor overall condition, right heart catheterization confirmed the diagnosis and murine double minute 2 positivity. Palliative care was implemented, and the patient died 13 days after admission. Our case underscores the importance of recognizing this sarcoma in pulmonary artery abnormalities, highlighting complementary roles of magnetic resonance–diffusion-weighted imaging in increasing prediagnostic probability and right heart catheterization in facilitating minimally invasive murine double minute 2 assessment. |
| format | Article |
| id | doaj-art-e4cc86ba43df4e7d83111303774b50bf |
| institution | OA Journals |
| issn | 2767-7664 |
| language | English |
| publishDate | 2024-07-01 |
| publisher | American College of Physicians |
| record_format | Article |
| series | Annals of Internal Medicine: Clinical Cases |
| spelling | doaj-art-e4cc86ba43df4e7d83111303774b50bf2025-08-20T02:11:45ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642024-07-013710.7326/aimcc.2023.1088Murine Double Minute 2–Positive Primary Pulmonary Artery Intimal Sarcoma Diagnosed by Pulmonary Arterial Catheter Aspiration After Emergency AdmissionMakoto Hibino0Shigehiro Watanabe1Riko Kamada2Shunichi Tobe3Kazunari Maeda4Shigeto Horiuchi5Noriyoshi Ishikawa6Tadashi Hasegawa7Tetsuri Kondo81Department of Respiratory Medicine, Shonan Fujisawa Tokushukai Hospital, Fujisawa, Japan1Department of Respiratory Medicine, Shonan Fujisawa Tokushukai Hospital, Fujisawa, Japan1Department of Respiratory Medicine, Shonan Fujisawa Tokushukai Hospital, Fujisawa, Japan1Department of Respiratory Medicine, Shonan Fujisawa Tokushukai Hospital, Fujisawa, Japan1Department of Respiratory Medicine, Shonan Fujisawa Tokushukai Hospital, Fujisawa, Japan1Department of Respiratory Medicine, Shonan Fujisawa Tokushukai Hospital, Fujisawa, Japan2Department of Pathology, Shonan Fujisawa Tokushukai Hospital, Fujisawa, Kanagawa, Japan3Department of Surgical Pathology, School of Medicine, Sapporo Medical University, Sapporo, Japan1Department of Respiratory Medicine, Shonan Fujisawa Tokushukai Hospital, Fujisawa, JapanWe present a rare case of primary pulmonary artery intimal sarcoma diagnosed after emergency admission for respiratory failure in an 80-year-old man. Tumor cells were obtained through minimally invasive pulmonary arterial catheter aspiration at a high-intensity magnetic resonance–diffusion-weighted imaging–highlighted site. Despite the patient's poor overall condition, right heart catheterization confirmed the diagnosis and murine double minute 2 positivity. Palliative care was implemented, and the patient died 13 days after admission. Our case underscores the importance of recognizing this sarcoma in pulmonary artery abnormalities, highlighting complementary roles of magnetic resonance–diffusion-weighted imaging in increasing prediagnostic probability and right heart catheterization in facilitating minimally invasive murine double minute 2 assessment.https://www.acpjournals.org/doi/10.7326/aimcc.2023.1088 |
| spellingShingle | Makoto Hibino Shigehiro Watanabe Riko Kamada Shunichi Tobe Kazunari Maeda Shigeto Horiuchi Noriyoshi Ishikawa Tadashi Hasegawa Tetsuri Kondo Murine Double Minute 2–Positive Primary Pulmonary Artery Intimal Sarcoma Diagnosed by Pulmonary Arterial Catheter Aspiration After Emergency Admission Annals of Internal Medicine: Clinical Cases |
| title | Murine Double Minute 2–Positive Primary Pulmonary Artery Intimal Sarcoma Diagnosed by Pulmonary Arterial Catheter Aspiration After Emergency Admission |
| title_full | Murine Double Minute 2–Positive Primary Pulmonary Artery Intimal Sarcoma Diagnosed by Pulmonary Arterial Catheter Aspiration After Emergency Admission |
| title_fullStr | Murine Double Minute 2–Positive Primary Pulmonary Artery Intimal Sarcoma Diagnosed by Pulmonary Arterial Catheter Aspiration After Emergency Admission |
| title_full_unstemmed | Murine Double Minute 2–Positive Primary Pulmonary Artery Intimal Sarcoma Diagnosed by Pulmonary Arterial Catheter Aspiration After Emergency Admission |
| title_short | Murine Double Minute 2–Positive Primary Pulmonary Artery Intimal Sarcoma Diagnosed by Pulmonary Arterial Catheter Aspiration After Emergency Admission |
| title_sort | murine double minute 2 positive primary pulmonary artery intimal sarcoma diagnosed by pulmonary arterial catheter aspiration after emergency admission |
| url | https://www.acpjournals.org/doi/10.7326/aimcc.2023.1088 |
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