Explainable deep learning for age and gender estimation in dental CBCT scans using attention mechanisms and multi task learning

Abstract Accurate and interpretable age estimation and gender classification are essential in forensic and clinical diagnostics, particularly when using high-dimensional medical imaging data such as Cone Beam Computed Tomography (CBCT). Traditional CBCT-based approaches often suffer from high comput...

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Main Authors: Najmeh Pishghadam, Rasool Esmaeilyfard, Maryam Paknahad
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-03305-z
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author Najmeh Pishghadam
Rasool Esmaeilyfard
Maryam Paknahad
author_facet Najmeh Pishghadam
Rasool Esmaeilyfard
Maryam Paknahad
author_sort Najmeh Pishghadam
collection DOAJ
description Abstract Accurate and interpretable age estimation and gender classification are essential in forensic and clinical diagnostics, particularly when using high-dimensional medical imaging data such as Cone Beam Computed Tomography (CBCT). Traditional CBCT-based approaches often suffer from high computational costs and limited interpretability, reducing their applicability in forensic investigations. This study aims to develop a multi-task deep learning framework that enhances both accuracy and explainability in CBCT-based age estimation and gender classification using attention mechanisms. We propose a multi-task learning (MTL) model that simultaneously estimates age and classifies gender using panoramic slices extracted from CBCT scans. To improve interpretability, we integrate Convolutional Block Attention Module (CBAM) and Grad-CAM visualization, highlighting relevant craniofacial regions. The dataset includes 2,426 CBCT images from individuals aged 7 to 23 years, and performance is assessed using Mean Absolute Error (MAE) for age estimation and accuracy for gender classification. The proposed model achieves a MAE of 1.08 years for age estimation and 95.3% accuracy in gender classification, significantly outperforming conventional CBCT-based methods. CBAM enhances the model’s ability to focus on clinically relevant anatomical features, while Grad-CAM provides visual explanations, improving interpretability. Additionally, using panoramic slices instead of full 3D CBCT volumes reduces computational costs without sacrificing accuracy. Our framework improves both accuracy and interpretability in forensic age estimation and gender classification from CBCT images. By incorporating explainable AI techniques, this model provides a computationally efficient and clinically interpretable tool for forensic and medical applications.
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spelling doaj-art-e4c0d35b36ac49c384434fe4c88b1dd22025-08-20T02:29:50ZengNature PortfolioScientific Reports2045-23222025-05-0115111010.1038/s41598-025-03305-zExplainable deep learning for age and gender estimation in dental CBCT scans using attention mechanisms and multi task learningNajmeh Pishghadam0Rasool Esmaeilyfard1Maryam Paknahad2Computer Engineering and Information Technology Department, Shiraz University of TechnologyComputer Engineering and Information Technology Department, Shiraz University of TechnologyOral and Dental Disease Research Center, Oral and Maxillofacial Radiology Department, Dental School, Shiraz University of Medical SciencesAbstract Accurate and interpretable age estimation and gender classification are essential in forensic and clinical diagnostics, particularly when using high-dimensional medical imaging data such as Cone Beam Computed Tomography (CBCT). Traditional CBCT-based approaches often suffer from high computational costs and limited interpretability, reducing their applicability in forensic investigations. This study aims to develop a multi-task deep learning framework that enhances both accuracy and explainability in CBCT-based age estimation and gender classification using attention mechanisms. We propose a multi-task learning (MTL) model that simultaneously estimates age and classifies gender using panoramic slices extracted from CBCT scans. To improve interpretability, we integrate Convolutional Block Attention Module (CBAM) and Grad-CAM visualization, highlighting relevant craniofacial regions. The dataset includes 2,426 CBCT images from individuals aged 7 to 23 years, and performance is assessed using Mean Absolute Error (MAE) for age estimation and accuracy for gender classification. The proposed model achieves a MAE of 1.08 years for age estimation and 95.3% accuracy in gender classification, significantly outperforming conventional CBCT-based methods. CBAM enhances the model’s ability to focus on clinically relevant anatomical features, while Grad-CAM provides visual explanations, improving interpretability. Additionally, using panoramic slices instead of full 3D CBCT volumes reduces computational costs without sacrificing accuracy. Our framework improves both accuracy and interpretability in forensic age estimation and gender classification from CBCT images. By incorporating explainable AI techniques, this model provides a computationally efficient and clinically interpretable tool for forensic and medical applications.https://doi.org/10.1038/s41598-025-03305-zCBCTMulti-task learningAttention mechanismsAge EstimationGender classificationExplainable AI (XAI)
spellingShingle Najmeh Pishghadam
Rasool Esmaeilyfard
Maryam Paknahad
Explainable deep learning for age and gender estimation in dental CBCT scans using attention mechanisms and multi task learning
Scientific Reports
CBCT
Multi-task learning
Attention mechanisms
Age Estimation
Gender classification
Explainable AI (XAI)
title Explainable deep learning for age and gender estimation in dental CBCT scans using attention mechanisms and multi task learning
title_full Explainable deep learning for age and gender estimation in dental CBCT scans using attention mechanisms and multi task learning
title_fullStr Explainable deep learning for age and gender estimation in dental CBCT scans using attention mechanisms and multi task learning
title_full_unstemmed Explainable deep learning for age and gender estimation in dental CBCT scans using attention mechanisms and multi task learning
title_short Explainable deep learning for age and gender estimation in dental CBCT scans using attention mechanisms and multi task learning
title_sort explainable deep learning for age and gender estimation in dental cbct scans using attention mechanisms and multi task learning
topic CBCT
Multi-task learning
Attention mechanisms
Age Estimation
Gender classification
Explainable AI (XAI)
url https://doi.org/10.1038/s41598-025-03305-z
work_keys_str_mv AT najmehpishghadam explainabledeeplearningforageandgenderestimationindentalcbctscansusingattentionmechanismsandmultitasklearning
AT rasoolesmaeilyfard explainabledeeplearningforageandgenderestimationindentalcbctscansusingattentionmechanismsandmultitasklearning
AT maryampaknahad explainabledeeplearningforageandgenderestimationindentalcbctscansusingattentionmechanismsandmultitasklearning