METTL3 blocked the progression of diabetic retinopathy through m6A-modified SOX2

METTL3 blocked the progression of diabetic retinopathy through m6A-modified SOX2

We aimed to explore the regulatory effects of methyltransferase-like 3 (METTL3) on diabetic retinopathy (DR) by regulating the m6A modification of SOX2 mRNA and elucidating the underlying molecular mechanism. The DR model was established by stimulating human retinal endothelial cells (HRECs) with hi...

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Bibliographic Details
Main Authors: Chen Xiujuan, Ling Qipeng, Xu Jie, Ye Yunyao, Dong Lili
Format: Article
Language:English
Published: De Gruyter 2025-07-01
Series:Open Medicine
Subjects:
diabetic retinopathy
mettl3
sox2
Online Access:https://doi.org/10.1515/med-2025-1191
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