Structure-Based Design of “Head-to-Tail” Macrocyclic PROTACs
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society
2024-11-01
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| Series: | JACS Au |
| Online Access: | https://doi.org/10.1021/jacsau.4c00831 |
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| _version_ | 1850134920481996800 |
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| author | Chungen Li Yihan Chen Weixue Huang Yudi Qiu Shengjie Huang Yang Zhou Fengtao Zhou Jian Xu Xiaomei Ren Jinwei Zhang Zhen Wang Ming Ding Ke Ding |
| author_facet | Chungen Li Yihan Chen Weixue Huang Yudi Qiu Shengjie Huang Yang Zhou Fengtao Zhou Jian Xu Xiaomei Ren Jinwei Zhang Zhen Wang Ming Ding Ke Ding |
| author_sort | Chungen Li |
| collection | DOAJ |
| format | Article |
| id | doaj-art-e4af2f80ee094493919a955d9dfb9f56 |
| institution | OA Journals |
| issn | 2691-3704 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | American Chemical Society |
| record_format | Article |
| series | JACS Au |
| spelling | doaj-art-e4af2f80ee094493919a955d9dfb9f562025-08-20T02:31:36ZengAmerican Chemical SocietyJACS Au2691-37042024-11-014124866488210.1021/jacsau.4c00831Structure-Based Design of “Head-to-Tail” Macrocyclic PROTACsChungen Li0Yihan Chen1Weixue Huang2Yudi Qiu3Shengjie Huang4Yang Zhou5Fengtao Zhou6Jian Xu7Xiaomei Ren8Jinwei Zhang9Zhen Wang10Ming Ding11Ke Ding12State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, ChinaState Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, ChinaState Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, ChinaKey Laboratory of Structure-Based Drugs Design and Discovery of Ministry of Education, Shengyang Pharmaceutical University, Shenyang, ChinaInternational Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Discovery of Chinese Ministry of Education (MOE), Guangzhou City Key Laboratory of Precision Chemical Drug Development, College of Pharmacy, Jinan University, Guangzhou, ChinaInternational Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Discovery of Chinese Ministry of Education (MOE), Guangzhou City Key Laboratory of Precision Chemical Drug Development, College of Pharmacy, Jinan University, Guangzhou, ChinaInternational Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Discovery of Chinese Ministry of Education (MOE), Guangzhou City Key Laboratory of Precision Chemical Drug Development, College of Pharmacy, Jinan University, Guangzhou, ChinaLivzon Research Institute, Livzon Pharmaceutical Group Inc., Zhuhai, ChinaState Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, ChinaState Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, ChinaState Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, ChinaSchool of Life Science and Technology, China Pharmaceutical University, Nanjing, ChinaState Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, Chinahttps://doi.org/10.1021/jacsau.4c00831 |
| spellingShingle | Chungen Li Yihan Chen Weixue Huang Yudi Qiu Shengjie Huang Yang Zhou Fengtao Zhou Jian Xu Xiaomei Ren Jinwei Zhang Zhen Wang Ming Ding Ke Ding Structure-Based Design of “Head-to-Tail” Macrocyclic PROTACs JACS Au |
| title | Structure-Based Design of “Head-to-Tail” Macrocyclic PROTACs |
| title_full | Structure-Based Design of “Head-to-Tail” Macrocyclic PROTACs |
| title_fullStr | Structure-Based Design of “Head-to-Tail” Macrocyclic PROTACs |
| title_full_unstemmed | Structure-Based Design of “Head-to-Tail” Macrocyclic PROTACs |
| title_short | Structure-Based Design of “Head-to-Tail” Macrocyclic PROTACs |
| title_sort | structure based design of head to tail macrocyclic protacs |
| url | https://doi.org/10.1021/jacsau.4c00831 |
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