Understanding the Feasibility to Implement Schistosomiasis Elimination Project Under China-Zimbabwe Cooperation: A Pilot Study Protocol

Abstract Background Schistosomiasis is one of the major neglected tropical diseases in Africa, accounting for approximately 90% of the global burden. In Zimbabwe, Schistosoma haematobium and S. mansoni infections are endemic. Although mass drug administration has been carried out among school-aged c...

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Main Authors: Yingjun Qian, Nicholas Midzi, Shizhu Li, Masceline Jenipher Mutsaka-Makuvaza, Shan Lv, Wei Ding, Zhiqiang Qin, Hongmei Li, Jie Zhou, Ling Tang, Changlian Li, Xinling Yu, Liang Shi, White Soko, Isaac Phiri, Cremance Tshuma, Munyaradzi Dobbie, Xiao-Nong Zhou
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Journal of Epidemiology and Global Health
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Online Access:https://doi.org/10.1007/s44197-025-00418-6
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author Yingjun Qian
Nicholas Midzi
Shizhu Li
Masceline Jenipher Mutsaka-Makuvaza
Shan Lv
Wei Ding
Zhiqiang Qin
Hongmei Li
Jie Zhou
Ling Tang
Changlian Li
Xinling Yu
Liang Shi
White Soko
Isaac Phiri
Cremance Tshuma
Munyaradzi Dobbie
Xiao-Nong Zhou
author_facet Yingjun Qian
Nicholas Midzi
Shizhu Li
Masceline Jenipher Mutsaka-Makuvaza
Shan Lv
Wei Ding
Zhiqiang Qin
Hongmei Li
Jie Zhou
Ling Tang
Changlian Li
Xinling Yu
Liang Shi
White Soko
Isaac Phiri
Cremance Tshuma
Munyaradzi Dobbie
Xiao-Nong Zhou
author_sort Yingjun Qian
collection DOAJ
description Abstract Background Schistosomiasis is one of the major neglected tropical diseases in Africa, accounting for approximately 90% of the global burden. In Zimbabwe, Schistosoma haematobium and S. mansoni infections are endemic. Although mass drug administration has been carried out among school-aged children, other interventions at the national level remain incomplete. China has established a public health cooperation mechanism with African countries targeting schistosomiasis and other infectious diseases. This study aims to conduct a pilot study to provide a methodological reference for large-scale surveys in similar settings. Method This pilot study served as an entry point for China-Africa cooperation in schistosomiasis control. A combination of cross-sectional studies and snail surveys was used. The survey was carried out in 14 villages of Chevakadzi ward in Zimbabwe. Households were selected through simple random sampling for the study. Fecal and urine samples were tested in the laboratory to diagnose schistosomiasis. Meanwhile, a capacity and needs assessment was conducted to understand the current situation of local disease control strategies. Discussion This study is expected to obtain important epidemiological information and indicators regarding the transmission of schistosomiasis at the sub-district level, providing a basis for judging the feasibility and practicality of large-scale China-Zimbabwe cooperation investments. The research results will also offer references for policy-making and the update of prevention and control strategies, contributing to schistosomiasis control in Zimbabwe. However, the study has limitations such as limited funding and difficulties in cross-border drug registration.
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spelling doaj-art-e4ac2e33529a45fba7a1895fc44813bf2025-08-20T02:39:04ZengSpringerJournal of Epidemiology and Global Health2210-60142025-05-0115111110.1007/s44197-025-00418-6Understanding the Feasibility to Implement Schistosomiasis Elimination Project Under China-Zimbabwe Cooperation: A Pilot Study ProtocolYingjun Qian0Nicholas Midzi1Shizhu Li2Masceline Jenipher Mutsaka-Makuvaza3Shan Lv4Wei Ding5Zhiqiang Qin6Hongmei Li7Jie Zhou8Ling Tang9Changlian Li10Xinling Yu11Liang Shi12White Soko13Isaac Phiri14Cremance Tshuma15Munyaradzi Dobbie16Xiao-Nong Zhou17National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research); National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases; Key Laboratory on Parasite and Vector Biology, Ministry of Health; WHO Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and TechnologyNational Institute of Health Research, Ministry of Health and Child CareNational Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research); National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases; Key Laboratory on Parasite and Vector Biology, Ministry of Health; WHO Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and TechnologyNational Institute of Health Research, Ministry of Health and Child CareNational Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research); National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases; Key Laboratory on Parasite and Vector Biology, Ministry of Health; WHO Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and TechnologyNational Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research); National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases; Key Laboratory on Parasite and Vector Biology, Ministry of Health; WHO Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and TechnologyNational Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research); National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases; Key Laboratory on Parasite and Vector Biology, Ministry of Health; WHO Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and TechnologyNational Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research); National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases; Key Laboratory on Parasite and Vector Biology, Ministry of Health; WHO Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and TechnologyHunan Institute of Schistosomiasis ControlHunan Institute of Schistosomiasis ControlHunan Institute of Schistosomiasis ControlHunan Institute of Schistosomiasis ControlJiangsu Institute of Parasitic DiseasesNational Institute of Health Research, Ministry of Health and Child CareEpidemiology and Disease Control, Ministry of Health and Child CareMashonaland Central Province, Ministry of Health and Child CarePublic Health Division, Ministry of Health and Child CareNational Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research); National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases; Key Laboratory on Parasite and Vector Biology, Ministry of Health; WHO Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and TechnologyAbstract Background Schistosomiasis is one of the major neglected tropical diseases in Africa, accounting for approximately 90% of the global burden. In Zimbabwe, Schistosoma haematobium and S. mansoni infections are endemic. Although mass drug administration has been carried out among school-aged children, other interventions at the national level remain incomplete. China has established a public health cooperation mechanism with African countries targeting schistosomiasis and other infectious diseases. This study aims to conduct a pilot study to provide a methodological reference for large-scale surveys in similar settings. Method This pilot study served as an entry point for China-Africa cooperation in schistosomiasis control. A combination of cross-sectional studies and snail surveys was used. The survey was carried out in 14 villages of Chevakadzi ward in Zimbabwe. Households were selected through simple random sampling for the study. Fecal and urine samples were tested in the laboratory to diagnose schistosomiasis. Meanwhile, a capacity and needs assessment was conducted to understand the current situation of local disease control strategies. Discussion This study is expected to obtain important epidemiological information and indicators regarding the transmission of schistosomiasis at the sub-district level, providing a basis for judging the feasibility and practicality of large-scale China-Zimbabwe cooperation investments. The research results will also offer references for policy-making and the update of prevention and control strategies, contributing to schistosomiasis control in Zimbabwe. However, the study has limitations such as limited funding and difficulties in cross-border drug registration.https://doi.org/10.1007/s44197-025-00418-6ChinaZimbabweSchistosomiasisEliminationAfricaTropical disease
spellingShingle Yingjun Qian
Nicholas Midzi
Shizhu Li
Masceline Jenipher Mutsaka-Makuvaza
Shan Lv
Wei Ding
Zhiqiang Qin
Hongmei Li
Jie Zhou
Ling Tang
Changlian Li
Xinling Yu
Liang Shi
White Soko
Isaac Phiri
Cremance Tshuma
Munyaradzi Dobbie
Xiao-Nong Zhou
Understanding the Feasibility to Implement Schistosomiasis Elimination Project Under China-Zimbabwe Cooperation: A Pilot Study Protocol
Journal of Epidemiology and Global Health
China
Zimbabwe
Schistosomiasis
Elimination
Africa
Tropical disease
title Understanding the Feasibility to Implement Schistosomiasis Elimination Project Under China-Zimbabwe Cooperation: A Pilot Study Protocol
title_full Understanding the Feasibility to Implement Schistosomiasis Elimination Project Under China-Zimbabwe Cooperation: A Pilot Study Protocol
title_fullStr Understanding the Feasibility to Implement Schistosomiasis Elimination Project Under China-Zimbabwe Cooperation: A Pilot Study Protocol
title_full_unstemmed Understanding the Feasibility to Implement Schistosomiasis Elimination Project Under China-Zimbabwe Cooperation: A Pilot Study Protocol
title_short Understanding the Feasibility to Implement Schistosomiasis Elimination Project Under China-Zimbabwe Cooperation: A Pilot Study Protocol
title_sort understanding the feasibility to implement schistosomiasis elimination project under china zimbabwe cooperation a pilot study protocol
topic China
Zimbabwe
Schistosomiasis
Elimination
Africa
Tropical disease
url https://doi.org/10.1007/s44197-025-00418-6
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