Evaluation of the antitumor activity of 2-[3-(2-chloroethyl)-3-nitrosoureido]-1,3-propanediol (chlonisol) in C57BL/6 mice with intracranially transplanted B16 melanoma

Evaluation of the antitumor activity of 2-[3-(2-chloroethyl)-3-nitrosoureido]-1,3-propanediol (chlonisol) in C57BL/6 mice with intracranially transplanted B16 melanoma

Background. The arsenal of antitumor drug therapy for melanoma brain metastases is limited. The search and study of new agents capable to penetrate the blood-brain barrier and provide a therapeutic effect against intracranial tumors remains an unmet clinical need. The aim is to evaluate the antitumo...

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Bibliographic Details
Main Authors:	I. G. Murazov, A. N. Stukov, Iu. G. Zmitrichenko, A. O. Niuganen, G. V. Tochilnikov, D. Ch. Latipova, L. V. Filatova, T. Yu. Semiglazova
Format:	Article
Language:	Russian
Published:	LLC “Publisher OKI” 2021-09-01
Series:	Фармакокинетика и Фармакодинамика
Subjects:	melanoma intracranial tumor brain metastases chlonisol preclinical studies
Online Access:	https://www.pharmacokinetica.ru/jour/article/view/251
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