Evaluating host diet effects on microparasites by measuring the stoichiometry of infrapopulations one cell at a time

Abstract Progress in the field of ecological stoichiometry has demonstrated that the outcome of ecological interactions can often be predicted a priori based on the nutrient ratios (e.g., carbon: nitrogen: phosphorus, C:N:P) of interacting organisms. However, the challenges of accurately measuring t...

Full description

Saved in:
Bibliographic Details
Main Authors: Charlotte F. Narr, Scott Binger, Erin Sedlacek, Bianca Anderson, Grace Shoemaker, Adrienne Stanley, Madison Stokoski, Ed Hall
Format: Article
Language:English
Published: Wiley 2024-07-01
Series:Ecology and Evolution
Subjects:
Online Access:https://doi.org/10.1002/ece3.11645
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849420614328123392
author Charlotte F. Narr
Scott Binger
Erin Sedlacek
Bianca Anderson
Grace Shoemaker
Adrienne Stanley
Madison Stokoski
Ed Hall
author_facet Charlotte F. Narr
Scott Binger
Erin Sedlacek
Bianca Anderson
Grace Shoemaker
Adrienne Stanley
Madison Stokoski
Ed Hall
author_sort Charlotte F. Narr
collection DOAJ
description Abstract Progress in the field of ecological stoichiometry has demonstrated that the outcome of ecological interactions can often be predicted a priori based on the nutrient ratios (e.g., carbon: nitrogen: phosphorus, C:N:P) of interacting organisms. However, the challenges of accurately measuring the nutrient content of active parasites within hosts has limited our ability to rigorously apply ecological stoichiometry to host–parasite systems. Traditional nutrient analyses require high parasite biomasses, often preventing individual‐level analyses. This prevents researchers from estimating variation in the nutrient content of individual parasites within a single host infrapopulation, a critical factor that could define how the ecology of the parasite affects the host–parasite interaction. Here, we explain how energy dispersive technology, a technique currently used to measure the elemental content of free‐living microbes, can be adapted for parasitic microbial infrapopulations. We demonstrate the power of accurately quantifying the biomass stoichiometry of individual microbial parasites sampled directly from individual hosts. Using this approach, we show that the stoichiometric composition of two microbial parasites capable of infecting the same host are stoichiometrically distinct and respond to host diet quality differently. We also demonstrate that characteristics of the stoichiometric trait distributions of these infrapopulations were important predictors of host fecundity, a proxy for virulence in this system, and better predictors of parasite load than the mean parasite stoichiometry or our parasite and diet treatments alone. EDS provides a rigorous tool for applying ecological stoichiometry to host–parasite systems and enables researchers to explore the nutritional physiology of host–parasite interactions at a scale that is more relevant to the ecology and evolution of the system than traditional nutrient analyses. Here we demonstrate that this level of resolution provides useful insights into the diet‐dependent physiology of microbial parasites and their hosts. We anticipate that this improved level of resolution has the potential to elucidate a range of eco–evo interactions in host–parasite systems that were previously unobservable.
format Article
id doaj-art-e4a95444531642ff94796f1bf7743edb
institution Kabale University
issn 2045-7758
language English
publishDate 2024-07-01
publisher Wiley
record_format Article
series Ecology and Evolution
spelling doaj-art-e4a95444531642ff94796f1bf7743edb2025-08-20T03:31:42ZengWileyEcology and Evolution2045-77582024-07-01147n/an/a10.1002/ece3.11645Evaluating host diet effects on microparasites by measuring the stoichiometry of infrapopulations one cell at a timeCharlotte F. Narr0Scott Binger1Erin Sedlacek2Bianca Anderson3Grace Shoemaker4Adrienne Stanley5Madison Stokoski6Ed Hall7School of Biological Sciences Southern Illinois University in Carbondale Carbondale Illinois USASchool of Biological Sciences Southern Illinois University in Carbondale Carbondale Illinois USASchool of Biological Sciences Southern Illinois University in Carbondale Carbondale Illinois USAEnvironmental Sciences and Sustainability Fort Collins Colorado USAEnvironmental Sciences and Sustainability Fort Collins Colorado USASchool of Biological Sciences Southern Illinois University in Carbondale Carbondale Illinois USASchool of Biological Sciences Southern Illinois University in Carbondale Carbondale Illinois USAEnvironmental Sciences and Sustainability Fort Collins Colorado USAAbstract Progress in the field of ecological stoichiometry has demonstrated that the outcome of ecological interactions can often be predicted a priori based on the nutrient ratios (e.g., carbon: nitrogen: phosphorus, C:N:P) of interacting organisms. However, the challenges of accurately measuring the nutrient content of active parasites within hosts has limited our ability to rigorously apply ecological stoichiometry to host–parasite systems. Traditional nutrient analyses require high parasite biomasses, often preventing individual‐level analyses. This prevents researchers from estimating variation in the nutrient content of individual parasites within a single host infrapopulation, a critical factor that could define how the ecology of the parasite affects the host–parasite interaction. Here, we explain how energy dispersive technology, a technique currently used to measure the elemental content of free‐living microbes, can be adapted for parasitic microbial infrapopulations. We demonstrate the power of accurately quantifying the biomass stoichiometry of individual microbial parasites sampled directly from individual hosts. Using this approach, we show that the stoichiometric composition of two microbial parasites capable of infecting the same host are stoichiometrically distinct and respond to host diet quality differently. We also demonstrate that characteristics of the stoichiometric trait distributions of these infrapopulations were important predictors of host fecundity, a proxy for virulence in this system, and better predictors of parasite load than the mean parasite stoichiometry or our parasite and diet treatments alone. EDS provides a rigorous tool for applying ecological stoichiometry to host–parasite systems and enables researchers to explore the nutritional physiology of host–parasite interactions at a scale that is more relevant to the ecology and evolution of the system than traditional nutrient analyses. Here we demonstrate that this level of resolution provides useful insights into the diet‐dependent physiology of microbial parasites and their hosts. We anticipate that this improved level of resolution has the potential to elucidate a range of eco–evo interactions in host–parasite systems that were previously unobservable.https://doi.org/10.1002/ece3.11645diet qualityelectron dispersive spectroscopyelemental compositioninfrapopulationsparasitestoichiometric trait distributions
spellingShingle Charlotte F. Narr
Scott Binger
Erin Sedlacek
Bianca Anderson
Grace Shoemaker
Adrienne Stanley
Madison Stokoski
Ed Hall
Evaluating host diet effects on microparasites by measuring the stoichiometry of infrapopulations one cell at a time
Ecology and Evolution
diet quality
electron dispersive spectroscopy
elemental composition
infrapopulations
parasite
stoichiometric trait distributions
title Evaluating host diet effects on microparasites by measuring the stoichiometry of infrapopulations one cell at a time
title_full Evaluating host diet effects on microparasites by measuring the stoichiometry of infrapopulations one cell at a time
title_fullStr Evaluating host diet effects on microparasites by measuring the stoichiometry of infrapopulations one cell at a time
title_full_unstemmed Evaluating host diet effects on microparasites by measuring the stoichiometry of infrapopulations one cell at a time
title_short Evaluating host diet effects on microparasites by measuring the stoichiometry of infrapopulations one cell at a time
title_sort evaluating host diet effects on microparasites by measuring the stoichiometry of infrapopulations one cell at a time
topic diet quality
electron dispersive spectroscopy
elemental composition
infrapopulations
parasite
stoichiometric trait distributions
url https://doi.org/10.1002/ece3.11645
work_keys_str_mv AT charlottefnarr evaluatinghostdieteffectsonmicroparasitesbymeasuringthestoichiometryofinfrapopulationsonecellatatime
AT scottbinger evaluatinghostdieteffectsonmicroparasitesbymeasuringthestoichiometryofinfrapopulationsonecellatatime
AT erinsedlacek evaluatinghostdieteffectsonmicroparasitesbymeasuringthestoichiometryofinfrapopulationsonecellatatime
AT biancaanderson evaluatinghostdieteffectsonmicroparasitesbymeasuringthestoichiometryofinfrapopulationsonecellatatime
AT graceshoemaker evaluatinghostdieteffectsonmicroparasitesbymeasuringthestoichiometryofinfrapopulationsonecellatatime
AT adriennestanley evaluatinghostdieteffectsonmicroparasitesbymeasuringthestoichiometryofinfrapopulationsonecellatatime
AT madisonstokoski evaluatinghostdieteffectsonmicroparasitesbymeasuringthestoichiometryofinfrapopulationsonecellatatime
AT edhall evaluatinghostdieteffectsonmicroparasitesbymeasuringthestoichiometryofinfrapopulationsonecellatatime