Simultaneously Cooperative, but Serially Antagonistic: A Neuropsychological Study of Diagonistic Dyspraxia in a Case of Marchiafava-Bignami Disease
We describe a patient with Marchiafava-Bignami disease who showed, in addition to signs of callosal interruption, a peculiar form of diagonistic dyspraxia. Unlike the typical diagonistic dyspraxia, both of the patient’s hands could simultaneously cooperate in a sequence of bimanual actions. More spe...
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| Format: | Article |
| Language: | English |
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Wiley
2008-01-01
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| Series: | Behavioural Neurology |
| Online Access: | http://dx.doi.org/10.1155/2008/845341 |
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| author | Kazumi Hirayama Kaori Tachibana Nobuhito Abe Hideaki Manabe Takahisa Fuse Tetsuro Tsukamoto |
| author_facet | Kazumi Hirayama Kaori Tachibana Nobuhito Abe Hideaki Manabe Takahisa Fuse Tetsuro Tsukamoto |
| author_sort | Kazumi Hirayama |
| collection | DOAJ |
| description | We describe a patient with Marchiafava-Bignami disease who showed, in addition to signs of callosal interruption, a peculiar form of diagonistic dyspraxia. Unlike the typical diagonistic dyspraxia, both of the patient’s hands could simultaneously cooperate in a sequence of bimanual actions. More specifically, his right hand could start a commanded action with the cooperation of his left hand. However, once the action was completed, his left hand started an antagonistic action, undoing the result, with the cooperation of his right hand. Once this countermanding action was completed, the original action started again. These antagonistic actions repeated themselves alternately unless he was restrained. The patient's diagonistic dyspraxia was apparent in only some bimanual actions, and he showed no diagonistic dyspraxia when performing voluntary actions; the antagonistic actions occurred in response to oral commands or by imitation. Magnetic resonance imaging showed symmetrical demyelination with partial necrosis in the genu, body, and anterior splenium of the corpus callosum. We speculate that the bimanual coordination is possible because part of the corpus callosum is intact, whereas the antagonistic actions may be caused by conflict between the two hemispheres due to interhemispheric disinhibition elicited by the demyelinated part of the corpus callosum. |
| format | Article |
| id | doaj-art-e4a5e45f18344187aa99b648ae54d944 |
| institution | Kabale University |
| issn | 0953-4180 1875-8584 |
| language | English |
| publishDate | 2008-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Behavioural Neurology |
| spelling | doaj-art-e4a5e45f18344187aa99b648ae54d9442025-08-20T03:26:25ZengWileyBehavioural Neurology0953-41801875-85842008-01-0119313714410.1155/2008/845341Simultaneously Cooperative, but Serially Antagonistic: A Neuropsychological Study of Diagonistic Dyspraxia in a Case of Marchiafava-Bignami DiseaseKazumi Hirayama0Kaori Tachibana1Nobuhito Abe2Hideaki Manabe3Takahisa Fuse4Tetsuro Tsukamoto5Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University Graduate School of Medicine, Sendai, JapanDepartment of Behavioral Neurology and Cognitive Neuroscience, Tohoku University Graduate School of Medicine, Sendai, JapanDepartment of Behavioral Neurology and Cognitive Neuroscience, Tohoku University Graduate School of Medicine, Sendai, JapanDepartment of Neurosurgery, National Hospital Organization, Shizuoka Medical Center, Shizuoka, JapanDepartment of Cardiovascular Surgery, National Hospital Organization, Shizuoka Medical Center, Shizuoka, JapanDepartment of Neurology, Numazu Rehabilitation Hospital, Numazu, JapanWe describe a patient with Marchiafava-Bignami disease who showed, in addition to signs of callosal interruption, a peculiar form of diagonistic dyspraxia. Unlike the typical diagonistic dyspraxia, both of the patient’s hands could simultaneously cooperate in a sequence of bimanual actions. More specifically, his right hand could start a commanded action with the cooperation of his left hand. However, once the action was completed, his left hand started an antagonistic action, undoing the result, with the cooperation of his right hand. Once this countermanding action was completed, the original action started again. These antagonistic actions repeated themselves alternately unless he was restrained. The patient's diagonistic dyspraxia was apparent in only some bimanual actions, and he showed no diagonistic dyspraxia when performing voluntary actions; the antagonistic actions occurred in response to oral commands or by imitation. Magnetic resonance imaging showed symmetrical demyelination with partial necrosis in the genu, body, and anterior splenium of the corpus callosum. We speculate that the bimanual coordination is possible because part of the corpus callosum is intact, whereas the antagonistic actions may be caused by conflict between the two hemispheres due to interhemispheric disinhibition elicited by the demyelinated part of the corpus callosum.http://dx.doi.org/10.1155/2008/845341 |
| spellingShingle | Kazumi Hirayama Kaori Tachibana Nobuhito Abe Hideaki Manabe Takahisa Fuse Tetsuro Tsukamoto Simultaneously Cooperative, but Serially Antagonistic: A Neuropsychological Study of Diagonistic Dyspraxia in a Case of Marchiafava-Bignami Disease Behavioural Neurology |
| title | Simultaneously Cooperative, but Serially Antagonistic: A Neuropsychological Study of Diagonistic Dyspraxia in a Case of Marchiafava-Bignami Disease |
| title_full | Simultaneously Cooperative, but Serially Antagonistic: A Neuropsychological Study of Diagonistic Dyspraxia in a Case of Marchiafava-Bignami Disease |
| title_fullStr | Simultaneously Cooperative, but Serially Antagonistic: A Neuropsychological Study of Diagonistic Dyspraxia in a Case of Marchiafava-Bignami Disease |
| title_full_unstemmed | Simultaneously Cooperative, but Serially Antagonistic: A Neuropsychological Study of Diagonistic Dyspraxia in a Case of Marchiafava-Bignami Disease |
| title_short | Simultaneously Cooperative, but Serially Antagonistic: A Neuropsychological Study of Diagonistic Dyspraxia in a Case of Marchiafava-Bignami Disease |
| title_sort | simultaneously cooperative but serially antagonistic a neuropsychological study of diagonistic dyspraxia in a case of marchiafava bignami disease |
| url | http://dx.doi.org/10.1155/2008/845341 |
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