Bicomponent Cutaneous Cell Therapy for Early Burn Care: Manufacturing Homogeneity and Epidermis-Structuring Functions of Clinical Grade FE002-SK2 Allogeneic Dermal Progenitor Fibroblasts

Bicomponent Cutaneous Cell Therapy for Early Burn Care: Manufacturing Homogeneity and Epidermis-Structuring Functions of Clinical Grade FE002-SK2 Allogeneic Dermal Progenitor Fibroblasts

<b>Background:</b> The extracellular matrix (ECM), primarily composed of collagen and elastin synthesized by dermal fibroblasts, is critical for mesenchymal tissue integrity. Fibroblast phenotypes vary significantly with the anatomical location and developmental stage. Fetal skin, partic...

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Bibliographic Details
Main Authors: Xi Chen, Nathalie Hirt-Burri, Corinne Scaletta, Alexis E. Laurent, Lee Ann Applegate
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Pharmaceutics
Subjects:
burns
cell banking
cell therapy
chronic wounds
extracellular matrix
fetal skin
Online Access:https://www.mdpi.com/1999-4923/17/6/692
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