Autophagy: a double-edged sword in ischemia–reperfusion injury

Autophagy: a double-edged sword in ischemia–reperfusion injury

Abstract Ischemia–reperfusion (I/R) injury describes the pathological process wherein tissue damage, initially caused by insufficient blood supply (ischemia), is exacerbated upon the restoration of blood flow (reperfusion). This phenomenon can lead to irreversible tissue damage and is commonly obser...

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Bibliographic Details
Main Authors: Lingxuan Tang, Wangzheqi Zhang, Yan Liao, Weijie Wang, Xiaoming Deng, Changli Wang, Wenwen Shi
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Cellular & Molecular Biology Letters
Subjects:
I/R injury
Autophagy
Mitophagy
Apoptosis
Necroptosis
Online Access:https://doi.org/10.1186/s11658-025-00713-x
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