Temporal Changes in Mitochondria-Centric Excitotoxic Responses Following Severe Penetrating Traumatic Brain Injury

Temporal Changes in Mitochondria-Centric Excitotoxic Responses Following Severe Penetrating Traumatic Brain Injury

<b>Background/Objectives:</b> Traumatic brain injury (TBI) remains a significant and urgent medical concern for the US military. TBI triggers excitotoxic responses immediately, involving mitochondrial dysfunction characterized by loss of calcium (Ca<sup>2+</sup>) cycling, mem...

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Bibliographic Details
Main Authors: Hiren R. Modi, Sudeep Musyaju, Anke H. Scultetus, Jignesh D. Pandya
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomedicines
Subjects:
severe traumatic brain injury
time course
mitochondrial damage
excitotoxicity
calcium homeostasis
cell death
Online Access:https://www.mdpi.com/2227-9059/13/7/1520
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