Mesalazine use tactics in the ulcerative colitis patients

Aim of the lecture. To specify indications for the administration of the 5-aminosalicylic acid (5-АSA) in the patients with ulcerative colitis (UC) and to discuss the possibility of correlation between the body mass index, the disease activity and reasonability for the prescription of the mesalazine...

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Main Authors: A. V. Korolev, O. Z. Okhlobystina, L. N. Androsova, O. S. Shifrin
Format: Article
Language:Russian
Published: Gastro LLC 2013-03-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
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Online Access:https://www.gastro-j.ru/jour/article/view/1185
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author A. V. Korolev
O. Z. Okhlobystina
L. N. Androsova
O. S. Shifrin
author_facet A. V. Korolev
O. Z. Okhlobystina
L. N. Androsova
O. S. Shifrin
author_sort A. V. Korolev
collection DOAJ
description Aim of the lecture. To specify indications for the administration of the 5-aminosalicylic acid (5-АSA) in the patients with ulcerative colitis (UC) and to discuss the possibility of correlation between the body mass index, the disease activity and reasonability for the prescription of the mesalazine (Pentasa) as a monotherapy.Key points. 5-АSA is the first line drug for the UC patients. The efficacy has been demonstrated in a huge number of studies, the indications for the administration have been determined and are dependent on the disease activity index. 5-АSA are used in moderate rate of the inflammatory activity. This article discusses the question of the possible relation between the body mass loss during the disease, www.m-vesti.ru and the body mass index as the additional factors for the determining of the pathological process activity and the indications for the prescription of the 5-АSA drugs. The article points out the possibility of the mesalazine rectal suppositories use for proctitis in the patients with UC that increases the adhesion of the patients to the treatment.Conclusion. Mesazaline is efficient in the UC patients with both distal as well as extended forms of the disease. The additional factor which determines the disease activity is probably the patients’ nutritional status which is expedient to be taken into account while selecting the therapy.
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publishDate 2013-03-01
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series Российский журнал гастроэнтерологии, гепатологии, колопроктологии
spelling doaj-art-e4871afabc844c5ba7372dad4ebc1efa2025-02-10T16:14:39ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732013-03-012315256769Mesalazine use tactics in the ulcerative colitis patientsA. V. Korolev0O. Z. Okhlobystina1L. N. Androsova2O. S. Shifrin3I.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityAim of the lecture. To specify indications for the administration of the 5-aminosalicylic acid (5-АSA) in the patients with ulcerative colitis (UC) and to discuss the possibility of correlation between the body mass index, the disease activity and reasonability for the prescription of the mesalazine (Pentasa) as a monotherapy.Key points. 5-АSA is the first line drug for the UC patients. The efficacy has been demonstrated in a huge number of studies, the indications for the administration have been determined and are dependent on the disease activity index. 5-АSA are used in moderate rate of the inflammatory activity. This article discusses the question of the possible relation between the body mass loss during the disease, www.m-vesti.ru and the body mass index as the additional factors for the determining of the pathological process activity and the indications for the prescription of the 5-АSA drugs. The article points out the possibility of the mesalazine rectal suppositories use for proctitis in the patients with UC that increases the adhesion of the patients to the treatment.Conclusion. Mesazaline is efficient in the UC patients with both distal as well as extended forms of the disease. The additional factor which determines the disease activity is probably the patients’ nutritional status which is expedient to be taken into account while selecting the therapy.https://www.gastro-j.ru/jour/article/view/1185ulcerative colitis5-aminosalicylic acidnutritional status
spellingShingle A. V. Korolev
O. Z. Okhlobystina
L. N. Androsova
O. S. Shifrin
Mesalazine use tactics in the ulcerative colitis patients
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
ulcerative colitis
5-aminosalicylic acid
nutritional status
title Mesalazine use tactics in the ulcerative colitis patients
title_full Mesalazine use tactics in the ulcerative colitis patients
title_fullStr Mesalazine use tactics in the ulcerative colitis patients
title_full_unstemmed Mesalazine use tactics in the ulcerative colitis patients
title_short Mesalazine use tactics in the ulcerative colitis patients
title_sort mesalazine use tactics in the ulcerative colitis patients
topic ulcerative colitis
5-aminosalicylic acid
nutritional status
url https://www.gastro-j.ru/jour/article/view/1185
work_keys_str_mv AT avkorolev mesalazineusetacticsintheulcerativecolitispatients
AT ozokhlobystina mesalazineusetacticsintheulcerativecolitispatients
AT lnandrosova mesalazineusetacticsintheulcerativecolitispatients
AT osshifrin mesalazineusetacticsintheulcerativecolitispatients