Chemistry and chemical biology tools contributing to the discovery and functional characterization of strigolactones
Strigolactones are a newly identified group of phytohormones that regulate plant growth and development and also act as communication signals in the rhizosphere. Beyond their well-known activity in stimulating parasitic weed germination, strigolactones function in regulating plant architecture, prom...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-06-01
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| Series: | Frontiers in Plant Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpls.2025.1618437/full |
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| author | Qian Zhou Changbin Niu Liang Feng Meixiu Dong Xiaoxu Li Xiaoxu Li Bo Kong Bo Kong Changsheng Li Changsheng Li |
| author_facet | Qian Zhou Changbin Niu Liang Feng Meixiu Dong Xiaoxu Li Xiaoxu Li Bo Kong Bo Kong Changsheng Li Changsheng Li |
| author_sort | Qian Zhou |
| collection | DOAJ |
| description | Strigolactones are a newly identified group of phytohormones that regulate plant growth and development and also act as communication signals in the rhizosphere. Beyond their well-known activity in stimulating parasitic weed germination, strigolactones function in regulating plant architecture, promoting symbiosis with arbuscular mycorrhizal fungi, and modulating responses to various environmental stresses. However, their low abundance, structural diversity, and instability have hindered comprehensive research and their practices. In this review, from the perspective of biological researcher, we summarize the powerful tools and strategies related to chemistry and chemical biology used in strigolactone area, covering analytical chemistry tools for isolation and structural elucidation, synthetic chemistry for structural elucidation and agricultural applications, chemical biology and biosynthetic strategies for functional characterization. Biosensors and probes used in monitoring strigolactone activity and signaling were also highlighted. Finally, we address current challenges and discuss future research perspectives, aiming to provoke more investigations on strigolactone biology and further boost their agricultural practices. |
| format | Article |
| id | doaj-art-e483feb26ffa4f05819bfa398749ca28 |
| institution | OA Journals |
| issn | 1664-462X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Plant Science |
| spelling | doaj-art-e483feb26ffa4f05819bfa398749ca282025-08-20T02:35:52ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2025-06-011610.3389/fpls.2025.16184371618437Chemistry and chemical biology tools contributing to the discovery and functional characterization of strigolactonesQian Zhou0Changbin Niu1Liang Feng2Meixiu Dong3Xiaoxu Li4Xiaoxu Li5Bo Kong6Bo Kong7Changsheng Li8Changsheng Li9Hunan Research Center of the Basic Discipline for Cell Signaling, Hunan Provincial Key Laboratory of Plant Functional Genomics and Developmental Regulation, College of Biology, Hunan University, Changsha, ChinaHunan Research Center of the Basic Discipline for Cell Signaling, Hunan Provincial Key Laboratory of Plant Functional Genomics and Developmental Regulation, College of Biology, Hunan University, Changsha, ChinaHunan Research Center of the Basic Discipline for Cell Signaling, Hunan Provincial Key Laboratory of Plant Functional Genomics and Developmental Regulation, College of Biology, Hunan University, Changsha, ChinaHunan Research Center of the Basic Discipline for Cell Signaling, Hunan Provincial Key Laboratory of Plant Functional Genomics and Developmental Regulation, College of Biology, Hunan University, Changsha, ChinaBeijing Life Science Academy, Beijing, ChinaTobacco Chemistry Research Institute of Technology Center, China Tobacco Hunan Industrial Co., Ltd., Changsha, ChinaBeijing Life Science Academy, Beijing, ChinaTobacco Chemistry Research Institute of Technology Center, China Tobacco Hunan Industrial Co., Ltd., Changsha, ChinaHunan Research Center of the Basic Discipline for Cell Signaling, Hunan Provincial Key Laboratory of Plant Functional Genomics and Developmental Regulation, College of Biology, Hunan University, Changsha, ChinaYuelushan Laboratory, Changsha, ChinaStrigolactones are a newly identified group of phytohormones that regulate plant growth and development and also act as communication signals in the rhizosphere. Beyond their well-known activity in stimulating parasitic weed germination, strigolactones function in regulating plant architecture, promoting symbiosis with arbuscular mycorrhizal fungi, and modulating responses to various environmental stresses. However, their low abundance, structural diversity, and instability have hindered comprehensive research and their practices. In this review, from the perspective of biological researcher, we summarize the powerful tools and strategies related to chemistry and chemical biology used in strigolactone area, covering analytical chemistry tools for isolation and structural elucidation, synthetic chemistry for structural elucidation and agricultural applications, chemical biology and biosynthetic strategies for functional characterization. Biosensors and probes used in monitoring strigolactone activity and signaling were also highlighted. Finally, we address current challenges and discuss future research perspectives, aiming to provoke more investigations on strigolactone biology and further boost their agricultural practices.https://www.frontiersin.org/articles/10.3389/fpls.2025.1618437/fullstrigolactonechemistrychemical biologybiosynthesisroot exudatesynthetic biology |
| spellingShingle | Qian Zhou Changbin Niu Liang Feng Meixiu Dong Xiaoxu Li Xiaoxu Li Bo Kong Bo Kong Changsheng Li Changsheng Li Chemistry and chemical biology tools contributing to the discovery and functional characterization of strigolactones Frontiers in Plant Science strigolactone chemistry chemical biology biosynthesis root exudate synthetic biology |
| title | Chemistry and chemical biology tools contributing to the discovery and functional characterization of strigolactones |
| title_full | Chemistry and chemical biology tools contributing to the discovery and functional characterization of strigolactones |
| title_fullStr | Chemistry and chemical biology tools contributing to the discovery and functional characterization of strigolactones |
| title_full_unstemmed | Chemistry and chemical biology tools contributing to the discovery and functional characterization of strigolactones |
| title_short | Chemistry and chemical biology tools contributing to the discovery and functional characterization of strigolactones |
| title_sort | chemistry and chemical biology tools contributing to the discovery and functional characterization of strigolactones |
| topic | strigolactone chemistry chemical biology biosynthesis root exudate synthetic biology |
| url | https://www.frontiersin.org/articles/10.3389/fpls.2025.1618437/full |
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