Bilateral intraocular masses in a child as a first presentation of disseminated tuberculosis: case report
An 8-year-old girl presented with left leukocoria, prompting an evaluation that revealed bilateral intraocular masses, including a right upper nasal choroidal lesion and a large left heterogeneous mass with exudative detachment. Imaging and systemic assessment uncovered multiple intracranial lesions...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2025-07-01
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| Series: | Therapeutic Advances in Ophthalmology |
| Online Access: | https://doi.org/10.1177/25158414251356373 |
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| author | Doaa Maamoun Ashour Nada Abdel Salam Abdel Aziz Khadiga Eltonbary Noha Abdul Khaliq Yasmeen Abdelaziz Fereig |
| author_facet | Doaa Maamoun Ashour Nada Abdel Salam Abdel Aziz Khadiga Eltonbary Noha Abdul Khaliq Yasmeen Abdelaziz Fereig |
| author_sort | Doaa Maamoun Ashour |
| collection | DOAJ |
| description | An 8-year-old girl presented with left leukocoria, prompting an evaluation that revealed bilateral intraocular masses, including a right upper nasal choroidal lesion and a large left heterogeneous mass with exudative detachment. Imaging and systemic assessment uncovered multiple intracranial lesions, miliary lung lesion, a facial lesion, and a right tibial lesion. A strongly positive tuberculin test and a history of close contact with a tuberculosis (TB) patient led to the diagnosis of disseminated TB. Treatment with anti-tuberculosis therapy and systemic steroids initially resulted in improvement, including regression of the ocular tuberculomas and enhanced visual acuity. However, the patient developed severe headache due to non-communicating obstructive hydrocephalus, necessitating surgical intervention. Despite intensive care, the patient ultimately succumbed to the condition. This case highlights that ocular TB lesions can mimic intraocular tumors and underscores the importance of comprehensive evaluation, including multimodal imaging and systemic work-up, for early diagnosis and management of disseminated TB. |
| format | Article |
| id | doaj-art-e47fdfc3ef4544439755afb3b9fbfaa0 |
| institution | DOAJ |
| issn | 2515-8414 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Therapeutic Advances in Ophthalmology |
| spelling | doaj-art-e47fdfc3ef4544439755afb3b9fbfaa02025-08-20T03:17:14ZengSAGE PublishingTherapeutic Advances in Ophthalmology2515-84142025-07-011710.1177/25158414251356373Bilateral intraocular masses in a child as a first presentation of disseminated tuberculosis: case reportDoaa Maamoun AshourNada Abdel Salam Abdel AzizKhadiga EltonbaryNoha Abdul KhaliqYasmeen Abdelaziz FereigAn 8-year-old girl presented with left leukocoria, prompting an evaluation that revealed bilateral intraocular masses, including a right upper nasal choroidal lesion and a large left heterogeneous mass with exudative detachment. Imaging and systemic assessment uncovered multiple intracranial lesions, miliary lung lesion, a facial lesion, and a right tibial lesion. A strongly positive tuberculin test and a history of close contact with a tuberculosis (TB) patient led to the diagnosis of disseminated TB. Treatment with anti-tuberculosis therapy and systemic steroids initially resulted in improvement, including regression of the ocular tuberculomas and enhanced visual acuity. However, the patient developed severe headache due to non-communicating obstructive hydrocephalus, necessitating surgical intervention. Despite intensive care, the patient ultimately succumbed to the condition. This case highlights that ocular TB lesions can mimic intraocular tumors and underscores the importance of comprehensive evaluation, including multimodal imaging and systemic work-up, for early diagnosis and management of disseminated TB.https://doi.org/10.1177/25158414251356373 |
| spellingShingle | Doaa Maamoun Ashour Nada Abdel Salam Abdel Aziz Khadiga Eltonbary Noha Abdul Khaliq Yasmeen Abdelaziz Fereig Bilateral intraocular masses in a child as a first presentation of disseminated tuberculosis: case report Therapeutic Advances in Ophthalmology |
| title | Bilateral intraocular masses in a child as a first presentation of disseminated tuberculosis: case report |
| title_full | Bilateral intraocular masses in a child as a first presentation of disseminated tuberculosis: case report |
| title_fullStr | Bilateral intraocular masses in a child as a first presentation of disseminated tuberculosis: case report |
| title_full_unstemmed | Bilateral intraocular masses in a child as a first presentation of disseminated tuberculosis: case report |
| title_short | Bilateral intraocular masses in a child as a first presentation of disseminated tuberculosis: case report |
| title_sort | bilateral intraocular masses in a child as a first presentation of disseminated tuberculosis case report |
| url | https://doi.org/10.1177/25158414251356373 |
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