Over-the-counter naproxen in rheumatology practice: scope and therapeutic benefits

Over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) contain a relatively low dose of their active ingredient and are intended for short-term use (for 3–5 days). They are effective and convenient in the treatment of musculoskeletal pain in many clinical situations in rheumatology practice....

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Main Authors: E. S. Filatova, A. E. Karateev
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2020-11-01
Series:Современная ревматология
Subjects:
Online Access:https://mrj.ima-press.net/mrj/article/view/1078
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author E. S. Filatova
A. E. Karateev
author_facet E. S. Filatova
A. E. Karateev
author_sort E. S. Filatova
collection DOAJ
description Over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) contain a relatively low dose of their active ingredient and are intended for short-term use (for 3–5 days). They are effective and convenient in the treatment of musculoskeletal pain in many clinical situations in rheumatology practice. Over-the-counter naproxen 275 mg has a proven analgesic efficacy, with its action duration of up to 12–15 hours after single-dose administration, and a favorable safety profile. It can be used successfully for the management of exacerbations of osteoarthritis, short-term episodes of pain with a stable course of autoimmune inflammatory rheumatic diseases, with acute nonspecific back pain and at the onset of periarticular soft tissue pathology. With allowance made for the national guidelines for the use of NSAIDs, this drug can be prescribed for a short time as an analgesic therapy in patients at high risk for cardiovascular events. It is of particular value for outpatient practice, since the patients can freely purchase and use it in accordance with the principles of responsible self-medication.
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series Современная ревматология
spelling doaj-art-e47cec17b0aa40258f540c8ff53594ec2025-08-20T03:59:54ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2020-11-0114412513110.14412/1996-7012-2020-4-125-1312306Over-the-counter naproxen in rheumatology practice: scope and therapeutic benefitsE. S. Filatova0A. E. Karateev1V.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyOver-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) contain a relatively low dose of their active ingredient and are intended for short-term use (for 3–5 days). They are effective and convenient in the treatment of musculoskeletal pain in many clinical situations in rheumatology practice. Over-the-counter naproxen 275 mg has a proven analgesic efficacy, with its action duration of up to 12–15 hours after single-dose administration, and a favorable safety profile. It can be used successfully for the management of exacerbations of osteoarthritis, short-term episodes of pain with a stable course of autoimmune inflammatory rheumatic diseases, with acute nonspecific back pain and at the onset of periarticular soft tissue pathology. With allowance made for the national guidelines for the use of NSAIDs, this drug can be prescribed for a short time as an analgesic therapy in patients at high risk for cardiovascular events. It is of particular value for outpatient practice, since the patients can freely purchase and use it in accordance with the principles of responsible self-medication.https://mrj.ima-press.net/mrj/article/view/1078nonsteroidal anti-inflammatory drugsnaproxennaproxen sodiumteraliv 275®efficiencysafetyrheumatic diseases
spellingShingle E. S. Filatova
A. E. Karateev
Over-the-counter naproxen in rheumatology practice: scope and therapeutic benefits
Современная ревматология
nonsteroidal anti-inflammatory drugs
naproxen
naproxen sodium
teraliv 275®
efficiency
safety
rheumatic diseases
title Over-the-counter naproxen in rheumatology practice: scope and therapeutic benefits
title_full Over-the-counter naproxen in rheumatology practice: scope and therapeutic benefits
title_fullStr Over-the-counter naproxen in rheumatology practice: scope and therapeutic benefits
title_full_unstemmed Over-the-counter naproxen in rheumatology practice: scope and therapeutic benefits
title_short Over-the-counter naproxen in rheumatology practice: scope and therapeutic benefits
title_sort over the counter naproxen in rheumatology practice scope and therapeutic benefits
topic nonsteroidal anti-inflammatory drugs
naproxen
naproxen sodium
teraliv 275®
efficiency
safety
rheumatic diseases
url https://mrj.ima-press.net/mrj/article/view/1078
work_keys_str_mv AT esfilatova overthecounternaproxeninrheumatologypracticescopeandtherapeuticbenefits
AT aekarateev overthecounternaproxeninrheumatologypracticescopeandtherapeuticbenefits