Issues of preparation for implementing uterine transplantation in clinical practice
The absolute uterine factor infertility is a non-treatable cause of female infertility. Surrogacy has become the only option that allows this group of patients to achieve genetic, although biological motherhood. According to statistics there are more than 30 thousand women of fertile age in Russia w...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department
2023-03-01
|
| Series: | Трансплантология (Москва) |
| Subjects: | |
| Online Access: | https://www.jtransplantologiya.ru/jour/article/view/747 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849409035013455872 |
|---|---|
| author | A. M. Polstianoy K. K. Gubarev O. Yu. Polstianaya I. V. Rendashkin |
| author_facet | A. M. Polstianoy K. K. Gubarev O. Yu. Polstianaya I. V. Rendashkin |
| author_sort | A. M. Polstianoy |
| collection | DOAJ |
| description | The absolute uterine factor infertility is a non-treatable cause of female infertility. Surrogacy has become the only option that allows this group of patients to achieve genetic, although biological motherhood. According to statistics there are more than 30 thousand women of fertile age in Russia who cannot get pregnant due to the absolute uterine factor infertility. The recently emerged possibility of uterine transplantation has become the only treatment for this kind of female infertility.Prior to the very first clinical study of human uterine transplantation which was carried out in 2013 in Sweden, scientists had conducted systematic studies in animals (rodents, pigs, cattle and primates). The first clinical trial with the uterine transplantation performed resulted in a live birth in September 2014. Currently, cases of successful uterine transplantation in humans have been reported in Sweden, Brazil, USA and Italy. Experience and practice in animal research played a key role in the success of the first clinical study on uterine transplantation. The application of this method is fundamental in the introduction of the scientifically grounded technology of uterine transplantation in Russia.Aim. Analysis of the problems of the clinical application of the uterine transplantation based on a literature review. |
| format | Article |
| id | doaj-art-e47ba002edf94781a00e25ce238848e3 |
| institution | Kabale University |
| issn | 2074-0506 2542-0909 |
| language | English |
| publishDate | 2023-03-01 |
| publisher | N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department |
| record_format | Article |
| series | Трансплантология (Москва) |
| spelling | doaj-art-e47ba002edf94781a00e25ce238848e32025-08-20T03:35:37ZengN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare DepartmentТрансплантология (Москва)2074-05062542-09092023-03-01151798810.23873/2074-0506-2023-15-1-79-88555Issues of preparation for implementing uterine transplantation in clinical practiceA. M. Polstianoy0K. K. Gubarev1O. Yu. Polstianaya2I. V. Rendashkin3Federal Siberian Research Clinical Centre of Federal Medical Biological AgencyState Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological AgencyFederal Siberian Research Clinical Centre of Federal Medical Biological AgencyFederal Siberian Research Clinical Centre of Federal Medical Biological AgencyThe absolute uterine factor infertility is a non-treatable cause of female infertility. Surrogacy has become the only option that allows this group of patients to achieve genetic, although biological motherhood. According to statistics there are more than 30 thousand women of fertile age in Russia who cannot get pregnant due to the absolute uterine factor infertility. The recently emerged possibility of uterine transplantation has become the only treatment for this kind of female infertility.Prior to the very first clinical study of human uterine transplantation which was carried out in 2013 in Sweden, scientists had conducted systematic studies in animals (rodents, pigs, cattle and primates). The first clinical trial with the uterine transplantation performed resulted in a live birth in September 2014. Currently, cases of successful uterine transplantation in humans have been reported in Sweden, Brazil, USA and Italy. Experience and practice in animal research played a key role in the success of the first clinical study on uterine transplantation. The application of this method is fundamental in the introduction of the scientifically grounded technology of uterine transplantation in Russia.Aim. Analysis of the problems of the clinical application of the uterine transplantation based on a literature review.https://www.jtransplantologiya.ru/jour/article/view/747uterine infertilityreproductive medicineassisted reproductive technologies |
| spellingShingle | A. M. Polstianoy K. K. Gubarev O. Yu. Polstianaya I. V. Rendashkin Issues of preparation for implementing uterine transplantation in clinical practice Трансплантология (Москва) uterine infertility reproductive medicine assisted reproductive technologies |
| title | Issues of preparation for implementing uterine transplantation in clinical practice |
| title_full | Issues of preparation for implementing uterine transplantation in clinical practice |
| title_fullStr | Issues of preparation for implementing uterine transplantation in clinical practice |
| title_full_unstemmed | Issues of preparation for implementing uterine transplantation in clinical practice |
| title_short | Issues of preparation for implementing uterine transplantation in clinical practice |
| title_sort | issues of preparation for implementing uterine transplantation in clinical practice |
| topic | uterine infertility reproductive medicine assisted reproductive technologies |
| url | https://www.jtransplantologiya.ru/jour/article/view/747 |
| work_keys_str_mv | AT ampolstianoy issuesofpreparationforimplementinguterinetransplantationinclinicalpractice AT kkgubarev issuesofpreparationforimplementinguterinetransplantationinclinicalpractice AT oyupolstianaya issuesofpreparationforimplementinguterinetransplantationinclinicalpractice AT ivrendashkin issuesofpreparationforimplementinguterinetransplantationinclinicalpractice |