Voltammetry Study of an Anti-HIV Compound by means of a Thin Organic Membrane
Cyclic and square wave voltammetries have been used to study electrochemical behaviour of an anti-HIV agent (Guttiferone A) at the liquid-liquid interface. The thin organic membrane is formed by an organic solvent containing redox probe. Guttiferone A, a benzophenone (BP) with appropriate electrolyt...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
|
| Series: | International Journal of Electrochemistry |
| Online Access: | http://dx.doi.org/10.1155/2013/902872 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850165988821041152 |
|---|---|
| author | Achille Nassi Thiery Christophe Ebelle Joseph M. Dika Manga Jules-Blaise Mabou Leuna Joel Donkeng Dazie Emmanuel Ngameni |
| author_facet | Achille Nassi Thiery Christophe Ebelle Joseph M. Dika Manga Jules-Blaise Mabou Leuna Joel Donkeng Dazie Emmanuel Ngameni |
| author_sort | Achille Nassi |
| collection | DOAJ |
| description | Cyclic and square wave voltammetries have been used to study electrochemical behaviour of an anti-HIV agent (Guttiferone A) at the liquid-liquid interface. The thin organic membrane is formed by an organic solvent containing redox probe. Guttiferone A, a benzophenone (BP) with appropriate electrolyte. It is demonstrated that BP possesses three reduction systems due to the redox transformation of the three tautomeric forms that lead to the migration of proton between the hydroxyl group in position 4 and the carbonyl group in positions 2 and 10. The transfer of proton from the aqueous solution to the organic phase is crucial for the redox transformation of BP into the organic membrane. The voltammograms obtained are strongly influenced by the pH of the aqueous phase. The electrochemical mechanism consists of 2e−/2H+ exchange to form the separate redox compound BPH2. |
| format | Article |
| id | doaj-art-e46d0f432f7747da95f4c8b3e5b823aa |
| institution | OA Journals |
| issn | 2090-3529 2090-3537 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Electrochemistry |
| spelling | doaj-art-e46d0f432f7747da95f4c8b3e5b823aa2025-08-20T02:21:34ZengWileyInternational Journal of Electrochemistry2090-35292090-35372013-01-01201310.1155/2013/902872902872Voltammetry Study of an Anti-HIV Compound by means of a Thin Organic MembraneAchille Nassi0Thiery Christophe Ebelle1Joseph M. Dika Manga2Jules-Blaise Mabou Leuna3Joel Donkeng Dazie4Emmanuel Ngameni5Laboratoire de Chimie Analytique, Faculté des Sciences, Université de Yaoundé 1, BP 812, Yaoundé, CameroonLaboratoire de Chimie Analytique, Faculté des Sciences, Université de Yaoundé 1, BP 812, Yaoundé, CameroonLaboratoire de Chimie Minérale, Faculté des Sciences, Université de Douala, BP 24157, Douala, CameroonLaboratoire de Chimie Analytique, Faculté des Sciences, Université de Yaoundé 1, BP 812, Yaoundé, CameroonLaboratoire de Chimie Analytique, Faculté des Sciences, Université de Yaoundé 1, BP 812, Yaoundé, CameroonLaboratoire de Chimie Analytique, Faculté des Sciences, Université de Yaoundé 1, BP 812, Yaoundé, CameroonCyclic and square wave voltammetries have been used to study electrochemical behaviour of an anti-HIV agent (Guttiferone A) at the liquid-liquid interface. The thin organic membrane is formed by an organic solvent containing redox probe. Guttiferone A, a benzophenone (BP) with appropriate electrolyte. It is demonstrated that BP possesses three reduction systems due to the redox transformation of the three tautomeric forms that lead to the migration of proton between the hydroxyl group in position 4 and the carbonyl group in positions 2 and 10. The transfer of proton from the aqueous solution to the organic phase is crucial for the redox transformation of BP into the organic membrane. The voltammograms obtained are strongly influenced by the pH of the aqueous phase. The electrochemical mechanism consists of 2e−/2H+ exchange to form the separate redox compound BPH2.http://dx.doi.org/10.1155/2013/902872 |
| spellingShingle | Achille Nassi Thiery Christophe Ebelle Joseph M. Dika Manga Jules-Blaise Mabou Leuna Joel Donkeng Dazie Emmanuel Ngameni Voltammetry Study of an Anti-HIV Compound by means of a Thin Organic Membrane International Journal of Electrochemistry |
| title | Voltammetry Study of an Anti-HIV Compound by means of a Thin Organic Membrane |
| title_full | Voltammetry Study of an Anti-HIV Compound by means of a Thin Organic Membrane |
| title_fullStr | Voltammetry Study of an Anti-HIV Compound by means of a Thin Organic Membrane |
| title_full_unstemmed | Voltammetry Study of an Anti-HIV Compound by means of a Thin Organic Membrane |
| title_short | Voltammetry Study of an Anti-HIV Compound by means of a Thin Organic Membrane |
| title_sort | voltammetry study of an anti hiv compound by means of a thin organic membrane |
| url | http://dx.doi.org/10.1155/2013/902872 |
| work_keys_str_mv | AT achillenassi voltammetrystudyofanantihivcompoundbymeansofathinorganicmembrane AT thierychristopheebelle voltammetrystudyofanantihivcompoundbymeansofathinorganicmembrane AT josephmdikamanga voltammetrystudyofanantihivcompoundbymeansofathinorganicmembrane AT julesblaisemabouleuna voltammetrystudyofanantihivcompoundbymeansofathinorganicmembrane AT joeldonkengdazie voltammetrystudyofanantihivcompoundbymeansofathinorganicmembrane AT emmanuelngameni voltammetrystudyofanantihivcompoundbymeansofathinorganicmembrane |