Safety and efficacy of incobotulinumtoxinA as a potential treatment for poststroke spasticity

Andrea Santamato Physical Medicine and Rehabilitation Section, “OORR Hospital,” University of Foggia, Foggia, Italy Abstract: Spasticity is a common disabling symptom for several neurological conditions. Botulinum toxin type A injection represents the gold standard trea...

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Main Author: Santamato A
Format: Article
Language:English
Published: Dove Medical Press 2016-01-01
Series:Neuropsychiatric Disease and Treatment
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Online Access:https://www.dovepress.com/safety-and-efficacy-of-incobotulinumtoxina-as-a-potential-treatment-fo-peer-reviewed-fulltext-article-NDT
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author Santamato A
author_facet Santamato A
author_sort Santamato A
collection DOAJ
description Andrea Santamato Physical Medicine and Rehabilitation Section, “OORR Hospital,” University of Foggia, Foggia, Italy Abstract: Spasticity is a common disabling symptom for several neurological conditions. Botulinum toxin type A injection represents the gold standard treatment for focal spasticity after stroke showing efficacy, reversibility, and low prevalence of complications. In recent years, incobotulinumtoxinA, a new Botulinum toxin type A free of complexing proteins, has been used for treating several movement disorders with safety and efficacy. IncobotulinumtoxinA is currently approved for treating spasticity of the upper limb in stroke survivors, even if several studies described the use also in lower limb muscles. In the present review article, we examine the safety and effectiveness of incobotulinumtoxinA for the treatment of spasticity after stroke. Keywords: Hypertone, botulinum toxin, incobotulinumtoxinA, onabotulinumtoxinA, abobotulinumtoxinA
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spelling doaj-art-e46bd5fa879f457d8d37e4d53f0039032025-08-20T03:30:03ZengDove Medical PressNeuropsychiatric Disease and Treatment1178-20212016-01-01Volume 12Issue 125126325395Safety and efficacy of incobotulinumtoxinA as a potential treatment for poststroke spasticitySantamato A0Physical Medicine and Rehabilitation SectionAndrea Santamato Physical Medicine and Rehabilitation Section, “OORR Hospital,” University of Foggia, Foggia, Italy Abstract: Spasticity is a common disabling symptom for several neurological conditions. Botulinum toxin type A injection represents the gold standard treatment for focal spasticity after stroke showing efficacy, reversibility, and low prevalence of complications. In recent years, incobotulinumtoxinA, a new Botulinum toxin type A free of complexing proteins, has been used for treating several movement disorders with safety and efficacy. IncobotulinumtoxinA is currently approved for treating spasticity of the upper limb in stroke survivors, even if several studies described the use also in lower limb muscles. In the present review article, we examine the safety and effectiveness of incobotulinumtoxinA for the treatment of spasticity after stroke. Keywords: Hypertone, botulinum toxin, incobotulinumtoxinA, onabotulinumtoxinA, abobotulinumtoxinAhttps://www.dovepress.com/safety-and-efficacy-of-incobotulinumtoxina-as-a-potential-treatment-fo-peer-reviewed-fulltext-article-NDTpost stroke-spasticitybotulinum toxinincobotulinumtoxinAonabotulinumtoxinAabobotulinumtoxinA
spellingShingle Santamato A
Safety and efficacy of incobotulinumtoxinA as a potential treatment for poststroke spasticity
Neuropsychiatric Disease and Treatment
post stroke-spasticity
botulinum toxin
incobotulinumtoxinA
onabotulinumtoxinA
abobotulinumtoxinA
title Safety and efficacy of incobotulinumtoxinA as a potential treatment for poststroke spasticity
title_full Safety and efficacy of incobotulinumtoxinA as a potential treatment for poststroke spasticity
title_fullStr Safety and efficacy of incobotulinumtoxinA as a potential treatment for poststroke spasticity
title_full_unstemmed Safety and efficacy of incobotulinumtoxinA as a potential treatment for poststroke spasticity
title_short Safety and efficacy of incobotulinumtoxinA as a potential treatment for poststroke spasticity
title_sort safety and efficacy of incobotulinumtoxina as a potential treatment for poststroke spasticity
topic post stroke-spasticity
botulinum toxin
incobotulinumtoxinA
onabotulinumtoxinA
abobotulinumtoxinA
url https://www.dovepress.com/safety-and-efficacy-of-incobotulinumtoxina-as-a-potential-treatment-fo-peer-reviewed-fulltext-article-NDT
work_keys_str_mv AT santamatoa safetyandefficacyofincobotulinumtoxinaasapotentialtreatmentforpoststrokespasticity