Lactitol may improve the prognosis of hepatocellular carcinoma through the proliferation of Megasphaera as well as Bifidobacterium

Lactitol may improve the prognosis of hepatocellular carcinoma through the proliferation of Megasphaera as well as Bifidobacterium

BackgroundIncreasing evidence suggests that gut microbiota and their metabolites can modulate antitumor immunity. However, sufficient evidence from human studies is lacking. We evaluated the association of lactitol and lactulose as prebiotics with the progression of hepatocellular carcinoma (HCC).Me...

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Bibliographic Details
Main Authors: Seigo Abiru, Yuki Kugiyama, Tomoyuki Suehiro, Yasuhide Motoyoshi, Akira Saeki, Shinya Nagaoka, Kazumi Yamasaki, Atsumasa Komori, Hiroshi Yatsuhashi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Medicine
Subjects:
HCC
prognosis
prebiotics
nonabosorbable disaccharides
gut microbiota
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1567849/full
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