Effect of regional living conditions on middle-term cardiovascular outcomes: data from prospective stage of the ESSE-RF study
Aim. To assess regional living conditions with cardiovascular outcomes based on prospective stage of the Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation (ESSE-RF) study.Material and methods. We used data from a 3- and 5-year prospective stage of the ES...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
«SILICEA-POLIGRAF» LLC
2021-09-01
|
| Series: | Кардиоваскулярная терапия и профилактика |
| Subjects: | |
| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/2965 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849698944404160512 |
|---|---|
| author | S. A. Maksimov S. A. Shalnova V. A. Kutsenko Yu. A. Balanova G. A. Muromtseva A. V. Kapustina S. E. Evstifeeva A. E. Imaeva N. S. Karamnova O. M. Drapkina |
| author_facet | S. A. Maksimov S. A. Shalnova V. A. Kutsenko Yu. A. Balanova G. A. Muromtseva A. V. Kapustina S. E. Evstifeeva A. E. Imaeva N. S. Karamnova O. M. Drapkina |
| author_sort | S. A. Maksimov |
| collection | DOAJ |
| description | Aim. To assess regional living conditions with cardiovascular outcomes based on prospective stage of the Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation (ESSE-RF) study.Material and methods. We used data from a 3- and 5-year prospective stage of the ESSE-RF study (2012-2013). For initial screening, 16210 people aged 25-64 were included. To characterize the regions of residence, 5 regional indices (RIs) were used. The following endpoints were considered: cardiovascular death, myocardial infarction, stroke, composite endpoint (cardiovascular death + myocardial infarction + stroke). To assess the correlations, generalized estimating equations with nested data structure (individuals in the regions) were used. The studied associations were adjusted for a wide range of potential effect modifiers.Results. There are multiple direct associations of RIs with the likelihood of all endpoints. The exception was the reverse association of Industrial RI with cardiovascular death. The most stable associations regarded Mixed RI, Industrial RI and Socio-geographical RI, with a high RI significance in endpoint development, compared with well-known individual cardiovascular risk factors. Separate associations were noted for Economic RI and Demographic RI.Conclusion. The results indicate a significant contribution of a number of regional living conditions to individual risk of fatal and non-fatal cardiovascular outcomes. |
| format | Article |
| id | doaj-art-e468b354611e4fe490431cb192bf2303 |
| institution | DOAJ |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2021-09-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-e468b354611e4fe490431cb192bf23032025-08-20T03:18:45Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252021-09-0120510.15829/1728-8800-2021-29652301Effect of regional living conditions on middle-term cardiovascular outcomes: data from prospective stage of the ESSE-RF studyS. A. Maksimov0S. A. Shalnova1V. A. Kutsenko2Yu. A. Balanova3G. A. Muromtseva4A. V. Kapustina5S. E. Evstifeeva6A. E. Imaeva7N. S. Karamnova8O. M. Drapkina9National Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineAim. To assess regional living conditions with cardiovascular outcomes based on prospective stage of the Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation (ESSE-RF) study.Material and methods. We used data from a 3- and 5-year prospective stage of the ESSE-RF study (2012-2013). For initial screening, 16210 people aged 25-64 were included. To characterize the regions of residence, 5 regional indices (RIs) were used. The following endpoints were considered: cardiovascular death, myocardial infarction, stroke, composite endpoint (cardiovascular death + myocardial infarction + stroke). To assess the correlations, generalized estimating equations with nested data structure (individuals in the regions) were used. The studied associations were adjusted for a wide range of potential effect modifiers.Results. There are multiple direct associations of RIs with the likelihood of all endpoints. The exception was the reverse association of Industrial RI with cardiovascular death. The most stable associations regarded Mixed RI, Industrial RI and Socio-geographical RI, with a high RI significance in endpoint development, compared with well-known individual cardiovascular risk factors. Separate associations were noted for Economic RI and Demographic RI.Conclusion. The results indicate a significant contribution of a number of regional living conditions to individual risk of fatal and non-fatal cardiovascular outcomes.https://cardiovascular.elpub.ru/jour/article/view/2965environmenthealth geographycardiovascular diseasesmyocardial infarctionstroke |
| spellingShingle | S. A. Maksimov S. A. Shalnova V. A. Kutsenko Yu. A. Balanova G. A. Muromtseva A. V. Kapustina S. E. Evstifeeva A. E. Imaeva N. S. Karamnova O. M. Drapkina Effect of regional living conditions on middle-term cardiovascular outcomes: data from prospective stage of the ESSE-RF study Кардиоваскулярная терапия и профилактика environment health geography cardiovascular diseases myocardial infarction stroke |
| title | Effect of regional living conditions on middle-term cardiovascular outcomes: data from prospective stage of the ESSE-RF study |
| title_full | Effect of regional living conditions on middle-term cardiovascular outcomes: data from prospective stage of the ESSE-RF study |
| title_fullStr | Effect of regional living conditions on middle-term cardiovascular outcomes: data from prospective stage of the ESSE-RF study |
| title_full_unstemmed | Effect of regional living conditions on middle-term cardiovascular outcomes: data from prospective stage of the ESSE-RF study |
| title_short | Effect of regional living conditions on middle-term cardiovascular outcomes: data from prospective stage of the ESSE-RF study |
| title_sort | effect of regional living conditions on middle term cardiovascular outcomes data from prospective stage of the esse rf study |
| topic | environment health geography cardiovascular diseases myocardial infarction stroke |
| url | https://cardiovascular.elpub.ru/jour/article/view/2965 |
| work_keys_str_mv | AT samaksimov effectofregionallivingconditionsonmiddletermcardiovascularoutcomesdatafromprospectivestageoftheesserfstudy AT sashalnova effectofregionallivingconditionsonmiddletermcardiovascularoutcomesdatafromprospectivestageoftheesserfstudy AT vakutsenko effectofregionallivingconditionsonmiddletermcardiovascularoutcomesdatafromprospectivestageoftheesserfstudy AT yuabalanova effectofregionallivingconditionsonmiddletermcardiovascularoutcomesdatafromprospectivestageoftheesserfstudy AT gamuromtseva effectofregionallivingconditionsonmiddletermcardiovascularoutcomesdatafromprospectivestageoftheesserfstudy AT avkapustina effectofregionallivingconditionsonmiddletermcardiovascularoutcomesdatafromprospectivestageoftheesserfstudy AT seevstifeeva effectofregionallivingconditionsonmiddletermcardiovascularoutcomesdatafromprospectivestageoftheesserfstudy AT aeimaeva effectofregionallivingconditionsonmiddletermcardiovascularoutcomesdatafromprospectivestageoftheesserfstudy AT nskaramnova effectofregionallivingconditionsonmiddletermcardiovascularoutcomesdatafromprospectivestageoftheesserfstudy AT omdrapkina effectofregionallivingconditionsonmiddletermcardiovascularoutcomesdatafromprospectivestageoftheesserfstudy |