EMB-driven glioblastoma multiforme progression via the MCT4/GPX3 axis: therapeutic inhibition by Ganxintriol A

EMB-driven glioblastoma multiforme progression via the MCT4/GPX3 axis: therapeutic inhibition by Ganxintriol A

Abstract Background Embigin (EMB) is a transmembrane glycoprotein highly expressed in glioblastoma multiforme (GBM), yet its role in GBM progression remains unclear. In this study, we investigate the function of intracellular EMB in promoting GBM progression and evaluate the effect of Ganxintriol A,...

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Bibliographic Details
Main Authors: Bo Cheng, Jing Liu, Ling Gao, Ziwen Zhu, Yang Yang, Shangqi Liu, Xiaojin Wu
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Translational Medicine
Online Access:https://doi.org/10.1186/s12967-025-06290-z
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