Oral Phenytoin Toxicity Causing Sinus Arrest: A Case Report
We present a case of sinus node arrest leading to symptomatic junctional bradycardia from oral phenytoin toxicity, which is a rare presentation. Our patient had no prior cardiac history and was on phenytoin therapy for seizure disorder. Although bradycardia is more commonly associated with intraveno...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2014/851767 |
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| author | Ravi K. Thimmisetty Janardhana Rao Gorthi Mahmoud Abu Hazeem |
| author_facet | Ravi K. Thimmisetty Janardhana Rao Gorthi Mahmoud Abu Hazeem |
| author_sort | Ravi K. Thimmisetty |
| collection | DOAJ |
| description | We present a case of sinus node arrest leading to symptomatic junctional bradycardia from oral phenytoin toxicity, which is a rare presentation. Our patient had no prior cardiac history and was on phenytoin therapy for seizure disorder. Although bradycardia is more commonly associated with intravenous phenytoin and there were few case reports of bradycardia with oral phenytoin reported, the literature is limited. In this case report, we also reviewed the pathophysiology of phenytoin-induced cardiac toxicity. |
| format | Article |
| id | doaj-art-e4619a0792264b83beb796bbce96eb49 |
| institution | Kabale University |
| issn | 2090-6404 2090-6412 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Cardiology |
| spelling | doaj-art-e4619a0792264b83beb796bbce96eb492025-08-20T03:26:27ZengWileyCase Reports in Cardiology2090-64042090-64122014-01-01201410.1155/2014/851767851767Oral Phenytoin Toxicity Causing Sinus Arrest: A Case ReportRavi K. Thimmisetty0Janardhana Rao Gorthi1Mahmoud Abu Hazeem2Department of Internal Medicine, Creighton University Medical Center, 601 N 30th Street, Omaha, NE 68131-0216, USADivision of Cardiology, University of Minnesota, Mayo Mail Code 508, 420 Delaware Street SE, Minneapolis, MN 55455, USADepartment of Internal Medicine, Creighton University Medical Center, 601 N 30th Street, Omaha, NE 68131-0216, USAWe present a case of sinus node arrest leading to symptomatic junctional bradycardia from oral phenytoin toxicity, which is a rare presentation. Our patient had no prior cardiac history and was on phenytoin therapy for seizure disorder. Although bradycardia is more commonly associated with intravenous phenytoin and there were few case reports of bradycardia with oral phenytoin reported, the literature is limited. In this case report, we also reviewed the pathophysiology of phenytoin-induced cardiac toxicity.http://dx.doi.org/10.1155/2014/851767 |
| spellingShingle | Ravi K. Thimmisetty Janardhana Rao Gorthi Mahmoud Abu Hazeem Oral Phenytoin Toxicity Causing Sinus Arrest: A Case Report Case Reports in Cardiology |
| title | Oral Phenytoin Toxicity Causing Sinus Arrest: A Case Report |
| title_full | Oral Phenytoin Toxicity Causing Sinus Arrest: A Case Report |
| title_fullStr | Oral Phenytoin Toxicity Causing Sinus Arrest: A Case Report |
| title_full_unstemmed | Oral Phenytoin Toxicity Causing Sinus Arrest: A Case Report |
| title_short | Oral Phenytoin Toxicity Causing Sinus Arrest: A Case Report |
| title_sort | oral phenytoin toxicity causing sinus arrest a case report |
| url | http://dx.doi.org/10.1155/2014/851767 |
| work_keys_str_mv | AT ravikthimmisetty oralphenytointoxicitycausingsinusarrestacasereport AT janardhanaraogorthi oralphenytointoxicitycausingsinusarrestacasereport AT mahmoudabuhazeem oralphenytointoxicitycausingsinusarrestacasereport |