Primary results of replacement the experimental hyaline cartilage defect with human fibroblast cell culture
The hyaline cartilage damage problem is actual, but existing recovery methods are not fully sufficient. A promising solution of this problem can be the implantation of a tissue-engineered structure (TEC), consisting of a cell culture and a biodegradable scaffold. In this experiment we created a cons...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | Russian |
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Private institution educational organization of higher education "Medical University "ReaViz"
2022-05-01
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| Series: | Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье |
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| Online Access: | https://vestnik.reaviz.ru/jour/article/view/424 |
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| author | M. S. Bozhokin D. M. Marchenko E. R. Mikhailova A. P. Antipov Yu. A. Nashchekina D. B. Vcherashnij S. V. Novoseltsev V. N. Kruglov |
| author_facet | M. S. Bozhokin D. M. Marchenko E. R. Mikhailova A. P. Antipov Yu. A. Nashchekina D. B. Vcherashnij S. V. Novoseltsev V. N. Kruglov |
| author_sort | M. S. Bozhokin |
| collection | DOAJ |
| description | The hyaline cartilage damage problem is actual, but existing recovery methods are not fully sufficient. A promising solution of this problem can be the implantation of a tissue-engineered structure (TEC), consisting of a cell culture and a biodegradable scaffold. In this experiment we created a construct consisting of a polylactide scaffold and a human dermal fibroblasts culture. After implantation of TEC in the modeled defect area we analyzed the experimental group regeneration results in comparison to the control group. |
| format | Article |
| id | doaj-art-e46063d5bf784fab95202a6b7f681173 |
| institution | DOAJ |
| issn | 2226-762X 2782-1579 |
| language | Russian |
| publishDate | 2022-05-01 |
| publisher | Private institution educational organization of higher education "Medical University "ReaViz" |
| record_format | Article |
| series | Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье |
| spelling | doaj-art-e46063d5bf784fab95202a6b7f6811732025-08-20T02:53:27ZrusPrivate institution educational organization of higher education "Medical University "ReaViz"Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье2226-762X2782-15792022-05-01122142110.20340/vmi-rvz.2022.2.MORPH.1306Primary results of replacement the experimental hyaline cartilage defect with human fibroblast cell cultureM. S. Bozhokin0D. M. Marchenko1E. R. Mikhailova2A. P. Antipov3Yu. A. Nashchekina4D. B. Vcherashnij5S. V. Novoseltsev6V. N. Kruglov7National Medical Research Center traumatology and orthopedics named after R.R. Vreden; Institute of Cytology Russian Academy of SciencesSaint Petersburg State UniversityInstitute of Cytology Russian Academy of SciencesNational Medical Research Center traumatology and orthopedics named after R.R. VredenInstitute of Cytology Russian Academy of SciencesIoffe Physical Technical InstituteI.M. Sechenov First Moscow State Medical UniversityReaviz Medical UniversityThe hyaline cartilage damage problem is actual, but existing recovery methods are not fully sufficient. A promising solution of this problem can be the implantation of a tissue-engineered structure (TEC), consisting of a cell culture and a biodegradable scaffold. In this experiment we created a construct consisting of a polylactide scaffold and a human dermal fibroblasts culture. After implantation of TEC in the modeled defect area we analyzed the experimental group regeneration results in comparison to the control group.https://vestnik.reaviz.ru/jour/article/view/424hyaline cartilagedefecttissue engineering constructionrecoverydermal fibroblasts |
| spellingShingle | M. S. Bozhokin D. M. Marchenko E. R. Mikhailova A. P. Antipov Yu. A. Nashchekina D. B. Vcherashnij S. V. Novoseltsev V. N. Kruglov Primary results of replacement the experimental hyaline cartilage defect with human fibroblast cell culture Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье hyaline cartilage defect tissue engineering construction recovery dermal fibroblasts |
| title | Primary results of replacement the experimental hyaline cartilage defect with human fibroblast cell culture |
| title_full | Primary results of replacement the experimental hyaline cartilage defect with human fibroblast cell culture |
| title_fullStr | Primary results of replacement the experimental hyaline cartilage defect with human fibroblast cell culture |
| title_full_unstemmed | Primary results of replacement the experimental hyaline cartilage defect with human fibroblast cell culture |
| title_short | Primary results of replacement the experimental hyaline cartilage defect with human fibroblast cell culture |
| title_sort | primary results of replacement the experimental hyaline cartilage defect with human fibroblast cell culture |
| topic | hyaline cartilage defect tissue engineering construction recovery dermal fibroblasts |
| url | https://vestnik.reaviz.ru/jour/article/view/424 |
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