Primary results of replacement the experimental hyaline cartilage defect with human fibroblast cell culture

Primary results of replacement the experimental hyaline cartilage defect with human fibroblast cell culture

The hyaline cartilage damage problem is actual, but existing recovery methods are not fully sufficient. A promising solution of this problem can be the implantation of a tissue-engineered structure (TEC), consisting of a cell culture and a biodegradable scaffold. In this experiment we created a cons...

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Bibliographic Details
Main Authors: M. S. Bozhokin, D. M. Marchenko, E. R. Mikhailova, A. P. Antipov, Yu. A. Nashchekina, D. B. Vcherashnij, S. V. Novoseltsev, V. N. Kruglov
Format: Article
Language:Russian
Published: Private institution educational organization of higher education "Medical University "ReaViz" 2022-05-01
Series:Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
Subjects:
hyaline cartilage
defect
tissue engineering construction
recovery
dermal fibroblasts
Online Access:https://vestnik.reaviz.ru/jour/article/view/424
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Summary:The hyaline cartilage damage problem is actual, but existing recovery methods are not fully sufficient. A promising solution of this problem can be the implantation of a tissue-engineered structure (TEC), consisting of a cell culture and a biodegradable scaffold. In this experiment we created a construct consisting of a polylactide scaffold and a human dermal fibroblasts culture. After implantation of TEC in the modeled defect area we analyzed the experimental group regeneration results in comparison to the control group.
ISSN:2226-762X
2782-1579

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