Marine natural product Methyl mycophenolate inhibits gastric cancer growth through regulating p53 and the downstream pathways

Marine natural product Methyl mycophenolate inhibits gastric cancer growth through regulating p53 and the downstream pathways

Abstract Background Gastric cancer (GC) is one of the most prevalent cancers and the fifth leading cause of cancer-related deaths globally. Methyl mycophenolate (MMP), a methyl ester derivative of mycophenolic acid, is derived from the marine fungus Phaeosphaeria spartinae, yet its role in GC remain...

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Bibliographic Details
Main Authors: Xiaofang Liu, Ning Xu, Jie Wang, Kaining Chen, Huiwen Ke, Yufen Xu, Dianying Feng, Lishi Xiao, Xiangqi Meng, Shi Chen, Hongyan Yu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cancer Cell International
Subjects:
Gastric cancer
Natural marine compounds
Methyl mycophenolate
p53
Ubiquitination
Online Access:https://doi.org/10.1186/s12935-025-03835-6
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https://doi.org/10.1186/s12935-025-03835-6

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