Calcified intracranial epidermoid cyst presented during pregnancy: A case report
We present the case of a 29-year-old female with a history of an intracranial tumor, initially diagnosed at age 22, who presented during her first pregnancy at 23 weeks with a seizure episode. MRI revealed a nonenhancing mass in the middle cranial fossa with high T1-weighted signal intensity. Despit...
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Elsevier
2025-08-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043325004017 |
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| author | Parisa Pishdad, MD Amirhossein Soltani, MD Amirmehdi Ghanbarzadeh, MD Shakiba Houshi, MD Mohsen Salimi, MD |
| author_facet | Parisa Pishdad, MD Amirhossein Soltani, MD Amirmehdi Ghanbarzadeh, MD Shakiba Houshi, MD Mohsen Salimi, MD |
| author_sort | Parisa Pishdad, MD |
| collection | DOAJ |
| description | We present the case of a 29-year-old female with a history of an intracranial tumor, initially diagnosed at age 22, who presented during her first pregnancy at 23 weeks with a seizure episode. MRI revealed a nonenhancing mass in the middle cranial fossa with high T1-weighted signal intensity. Despite concerns regarding the potential for eclampsia, the patient was conservatively managed with seizure prophylaxis, and a cesarean section was performed at 38 weeks’ gestation. Over the following years, the patient experienced stable imaging findings and mild headaches but later developed worsening symptoms due to mass effect, requiring a Ventriculoperitoneal shunt and subsequent tumor resection. Pathology confirmed the diagnosis of an epidermoid cyst. This case highlights the importance of a multidisciplinary approach to managing intracranial lesions in pregnancy, as early diagnosis and careful coordination between obstetrics, neurology, and neurosurgery teams are crucial to ensuring optimal maternal and fetal outcomes. Additionally, it underscores the need for long-term follow-up in patients with brain lesions during pregnancy, as complications may arise years later, necessitating timely interventions. Notably, this case also demonstrates unique characteristics of an epidermoid cyst with high T1-weighted signal and hyperdensity on CT that remained unchanged over time, favoring the diagnosis of a calcified epidermoid cyst—a rare entity. |
| format | Article |
| id | doaj-art-e452f337f38f4ca68e785e7dfdad9f19 |
| institution | OA Journals |
| issn | 1930-0433 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj-art-e452f337f38f4ca68e785e7dfdad9f192025-08-20T02:30:55ZengElsevierRadiology Case Reports1930-04332025-08-012083738374310.1016/j.radcr.2025.04.103Calcified intracranial epidermoid cyst presented during pregnancy: A case reportParisa Pishdad, MD0Amirhossein Soltani, MD1Amirmehdi Ghanbarzadeh, MD2Shakiba Houshi, MD3Mohsen Salimi, MD4Department of Radiology, Shiraz University of Medical Sciences, Shiraz, Iran; Medical Imaging Research Center, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Radiology, Shiraz University of Medical Sciences, Shiraz, Iran; Medical Imaging Research Center, Shiraz University of Medical Sciences, Shiraz, IranSchool of Medicine, Shiraz University of Medical Sciences, Shiraz, IranIsfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, IranSchool of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran; Corresponding author.We present the case of a 29-year-old female with a history of an intracranial tumor, initially diagnosed at age 22, who presented during her first pregnancy at 23 weeks with a seizure episode. MRI revealed a nonenhancing mass in the middle cranial fossa with high T1-weighted signal intensity. Despite concerns regarding the potential for eclampsia, the patient was conservatively managed with seizure prophylaxis, and a cesarean section was performed at 38 weeks’ gestation. Over the following years, the patient experienced stable imaging findings and mild headaches but later developed worsening symptoms due to mass effect, requiring a Ventriculoperitoneal shunt and subsequent tumor resection. Pathology confirmed the diagnosis of an epidermoid cyst. This case highlights the importance of a multidisciplinary approach to managing intracranial lesions in pregnancy, as early diagnosis and careful coordination between obstetrics, neurology, and neurosurgery teams are crucial to ensuring optimal maternal and fetal outcomes. Additionally, it underscores the need for long-term follow-up in patients with brain lesions during pregnancy, as complications may arise years later, necessitating timely interventions. Notably, this case also demonstrates unique characteristics of an epidermoid cyst with high T1-weighted signal and hyperdensity on CT that remained unchanged over time, favoring the diagnosis of a calcified epidermoid cyst—a rare entity.http://www.sciencedirect.com/science/article/pii/S1930043325004017Brain tumorCalcified epidermoid cystIntracranial epidermoid cystPregnancy |
| spellingShingle | Parisa Pishdad, MD Amirhossein Soltani, MD Amirmehdi Ghanbarzadeh, MD Shakiba Houshi, MD Mohsen Salimi, MD Calcified intracranial epidermoid cyst presented during pregnancy: A case report Radiology Case Reports Brain tumor Calcified epidermoid cyst Intracranial epidermoid cyst Pregnancy |
| title | Calcified intracranial epidermoid cyst presented during pregnancy: A case report |
| title_full | Calcified intracranial epidermoid cyst presented during pregnancy: A case report |
| title_fullStr | Calcified intracranial epidermoid cyst presented during pregnancy: A case report |
| title_full_unstemmed | Calcified intracranial epidermoid cyst presented during pregnancy: A case report |
| title_short | Calcified intracranial epidermoid cyst presented during pregnancy: A case report |
| title_sort | calcified intracranial epidermoid cyst presented during pregnancy a case report |
| topic | Brain tumor Calcified epidermoid cyst Intracranial epidermoid cyst Pregnancy |
| url | http://www.sciencedirect.com/science/article/pii/S1930043325004017 |
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