Analysis of Postoperative Bleeding After Oral Surgery in Patients Receiving Anticoagulants: A Retrospective Study
<i>Background and Objectives</i>: Patients taking anticoagulants, particularly warfarin and non-vitamin K oral anticoagulants (NOACs), face an elevated risk of postoperative bleeding during minor oral surgeries, highlighting the urgent need to identify reliable predictors for bleeding co...
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MDPI AG
2025-02-01
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| author | Jae-Il Lee Hyejun Seo Yeong-Cheol Cho Jang-Ho Son Iel-Yong Sung |
| author_facet | Jae-Il Lee Hyejun Seo Yeong-Cheol Cho Jang-Ho Son Iel-Yong Sung |
| author_sort | Jae-Il Lee |
| collection | DOAJ |
| description | <i>Background and Objectives</i>: Patients taking anticoagulants, particularly warfarin and non-vitamin K oral anticoagulants (NOACs), face an elevated risk of postoperative bleeding during minor oral surgeries, highlighting the urgent need to identify reliable predictors for bleeding complications. In this study, we evaluated the effectiveness of predictors of bleeding complications in patients receiving anticoagulants who underwent minor oral surgeries. <i>Materials and Methods</i>: The electronic medical and dental records of 206 patients who underwent oral surgery at the University of Ulsan Hospital between 2015 and 2023 were retrospectively reviewed. Patients were categorized into those taking warfarin and those taking NOACs, and postoperative bleeding was determined. Risk factors were statistically analyzed using the chi-square or Fisher’s exact test and Student’s t-test. <i>Results</i>: Among the 206 patients (86 on warfarin, 120 on NOACs), 84 (36 on warfarin, 48 on NOACs) experienced bleeding complications following their procedures. Time in the therapeutic range (TTR) and international normalized ratio (INR) values were significantly associated with bleeding complications in the warfarin group, while the type of NOAC was associated with bleeding in the NOAC group. Perioperative bleeding was significantly correlated with postoperative bleeding in both groups. <i>Conclusions</i>: Taken together, these findings highlight the correlations between postoperative bleeding and specific factors associated with anticoagulant drugs in patients that underwent oral surgery. Identifying these predictors can improve patient management by enhancing pre- and perioperative assessments, reducing the risk of bleeding, and optimizing surgical outcomes. |
| format | Article |
| id | doaj-art-e44ba9721258484abc884c18c700c221 |
| institution | OA Journals |
| issn | 1010-660X 1648-9144 |
| language | English |
| publishDate | 2025-02-01 |
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| series | Medicina |
| spelling | doaj-art-e44ba9721258484abc884c18c700c2212025-08-20T02:11:08ZengMDPI AGMedicina1010-660X1648-91442025-02-0161342510.3390/medicina61030425Analysis of Postoperative Bleeding After Oral Surgery in Patients Receiving Anticoagulants: A Retrospective StudyJae-Il Lee0Hyejun Seo1Yeong-Cheol Cho2Jang-Ho Son3Iel-Yong Sung4Department of Dentistry, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan 44033, Republic of KoreaDepartment of Dentistry, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan 44033, Republic of KoreaDepartment of Oral and Maxillofacial Surgery, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan 44033, Republic of KoreaDepartment of Oral and Maxillofacial Surgery, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan 44033, Republic of KoreaDepartment of Oral and Maxillofacial Surgery, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan 44033, Republic of Korea<i>Background and Objectives</i>: Patients taking anticoagulants, particularly warfarin and non-vitamin K oral anticoagulants (NOACs), face an elevated risk of postoperative bleeding during minor oral surgeries, highlighting the urgent need to identify reliable predictors for bleeding complications. In this study, we evaluated the effectiveness of predictors of bleeding complications in patients receiving anticoagulants who underwent minor oral surgeries. <i>Materials and Methods</i>: The electronic medical and dental records of 206 patients who underwent oral surgery at the University of Ulsan Hospital between 2015 and 2023 were retrospectively reviewed. Patients were categorized into those taking warfarin and those taking NOACs, and postoperative bleeding was determined. Risk factors were statistically analyzed using the chi-square or Fisher’s exact test and Student’s t-test. <i>Results</i>: Among the 206 patients (86 on warfarin, 120 on NOACs), 84 (36 on warfarin, 48 on NOACs) experienced bleeding complications following their procedures. Time in the therapeutic range (TTR) and international normalized ratio (INR) values were significantly associated with bleeding complications in the warfarin group, while the type of NOAC was associated with bleeding in the NOAC group. Perioperative bleeding was significantly correlated with postoperative bleeding in both groups. <i>Conclusions</i>: Taken together, these findings highlight the correlations between postoperative bleeding and specific factors associated with anticoagulant drugs in patients that underwent oral surgery. Identifying these predictors can improve patient management by enhancing pre- and perioperative assessments, reducing the risk of bleeding, and optimizing surgical outcomes.https://www.mdpi.com/1648-9144/61/3/425bleedingoral anticoagulantsoral surgerywarfarinnon-vitamin K oral anticoagulants |
| spellingShingle | Jae-Il Lee Hyejun Seo Yeong-Cheol Cho Jang-Ho Son Iel-Yong Sung Analysis of Postoperative Bleeding After Oral Surgery in Patients Receiving Anticoagulants: A Retrospective Study Medicina bleeding oral anticoagulants oral surgery warfarin non-vitamin K oral anticoagulants |
| title | Analysis of Postoperative Bleeding After Oral Surgery in Patients Receiving Anticoagulants: A Retrospective Study |
| title_full | Analysis of Postoperative Bleeding After Oral Surgery in Patients Receiving Anticoagulants: A Retrospective Study |
| title_fullStr | Analysis of Postoperative Bleeding After Oral Surgery in Patients Receiving Anticoagulants: A Retrospective Study |
| title_full_unstemmed | Analysis of Postoperative Bleeding After Oral Surgery in Patients Receiving Anticoagulants: A Retrospective Study |
| title_short | Analysis of Postoperative Bleeding After Oral Surgery in Patients Receiving Anticoagulants: A Retrospective Study |
| title_sort | analysis of postoperative bleeding after oral surgery in patients receiving anticoagulants a retrospective study |
| topic | bleeding oral anticoagulants oral surgery warfarin non-vitamin K oral anticoagulants |
| url | https://www.mdpi.com/1648-9144/61/3/425 |
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